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参加国家乳腺癌和宫颈癌早期检测项目的女性与未参加该项目的女性之间乳腺癌分期的比较分析。

A comparative analysis of breast cancer stage between women enrolled in the National Breast and Cervical Cancer Early Detection Program and women not participating in the program.

作者信息

Wu Manxia, Austin Harland, Eheman Christie R, Myles Zachary, Miller Jacqueline, Royalty Janet, Ryerson A Blythe

机构信息

Centers for Disease Control and Prevention, Atlanta, GA, USA,

出版信息

Cancer Causes Control. 2015 May;26(5):751-8. doi: 10.1007/s10552-015-0548-x. Epub 2015 Mar 12.

Abstract

PURPOSE

To determine the proportional distribution of early- and late-stage breast cancers diagnosed in years 2004-2009 among women enrolled in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) and to compare this distribution to that of geographically comparable non-enrolled women diagnosed with breast cancer.

METHODS

Using data from the National Program of Cancer Registries, we compared the demographic characteristics and cancer stage distribution of women enrollees and non-enrollees by use of conditional logistic regression using the odds ratio as a measure of association.

RESULTS

NBCCEDP enrollees were slightly younger and more likely to identify as African-American, API and AIAN than were non-enrollees. The proportion of late-stage breast cancer (regional and distant) decreased slightly over the study period. NBCCEDP enrollees generally were diagnosed at a later stage of breast cancer than were those not enrolled in the NBCCEDP.

CONCLUSIONS

The NBCCEDP has been effective in achieving its goal of enrolling racial and ethnic populations; however, enrollees had a poorer stage distribution of breast cancer than did non-enrollees underscoring the need to expand breast cancer control efforts among low-income, underserved populations.

摘要

目的

确定2004 - 2009年期间在国家乳腺癌和宫颈癌早期检测项目(NBCCEDP)登记的女性中早期和晚期乳腺癌的比例分布,并将此分布与地理上可比的未登记的乳腺癌确诊女性的分布进行比较。

方法

利用国家癌症登记项目的数据,我们通过使用比值比作为关联度量的条件逻辑回归,比较了登记女性和未登记女性的人口统计学特征和癌症分期分布。

结果

与未登记者相比,NBCCEDP登记者年龄稍小,更有可能认定自己为非裔美国人、亚太裔和美国印第安人和阿拉斯加原住民。在研究期间,晚期乳腺癌(区域性和远处性)的比例略有下降。NBCCEDP登记者通常比未登记参加NBCCEDP的人被诊断出乳腺癌的阶段更晚。

结论

NBCCEDP在实现其登记种族和族裔人群的目标方面是有效的;然而,登记者的乳腺癌分期分布比未登记者差,这突出表明需要在低收入、服务不足的人群中加大乳腺癌控制力度。

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