Popov Aron-Frederik, García Sáez Diana, Sabashnikov Anton, Patil Nikhil P, Zeriouh Mohamed, Mohite Prashant N, Zych Bartlomiej, Schmack Bastian, Ruhparwar Arjang, Kallenbach Klaus, Dohmen Pascal M, Karck Matthias, Simon Andre R, Weymann Alexander
Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.
Department of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
Med Sci Monit Basic Res. 2015 Mar 12;21:29-32. doi: 10.12659/MSMBR.894020.
For patients with end-stage heart failure, cardiac transplantation persists to be the gold standard. Nevertheless, the availability of organs remains a main constraint to the treatment. Through mounting usage of ex vivo heart perfusion an increase in organ availability was achieved by reconditioning of organs formerly not regarded as appropriate for transplantation. We propose the future standard application of this state-of-the-art technology to improve the pool of donor organs by evaluating hearts outside standard acceptability criteria.
对于终末期心力衰竭患者,心脏移植仍然是金标准。然而,器官的可获得性仍然是治疗的主要限制因素。通过越来越多地使用离体心脏灌注技术,对以前被认为不适合移植的器官进行修复,从而提高了器官的可获得性。我们建议未来将这种先进技术作为标准应用,通过评估超出标准可接受标准的心脏来改善供体器官库。