Jensen L L, Baratt-Due A, Englund P N, Harju J A, Sigurðsson T S, Liberg J-P
Department of Anaesthesia and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Acta Anaesthesiol Scand. 2015 May;59(5):568-75. doi: 10.1111/aas.12500. Epub 2015 Mar 12.
Treatment of acute respiratory distress syndrome (ARDS) in children is largely based on extrapolated knowledge obtained from adults and which varies between different hospitals. This study explores ventilation treatment strategies for children with ARDS in the Nordic countries, and compares these with international practice.
In October 2012, a questionnaire covering ventilation treatment strategies for children aged 1 month to 6 years of age with ARDS was sent to 21 large Nordic intensive care units that treat children with ARDS. Pre-terms and children with congenital conditions were excluded.
Eighteen of the 21 (86%) targeted intensive care units responded to the questionnaire. Fifty per cent of these facilities were paediatric intensive care units. Written guidelines existed in 44% of the units. Fifty per cent of the units frequently used cuffed endotracheal tubes. Ventilation was achieved by pressure control for 89% vs. volume control for 11% of units. Bronchodilators were used by all units, whereas steroids usage was 83% and surfactant 39%. Inhaled nitric oxide and high frequency oscillation were available in 94% of the units. Neurally adjusted ventilator assist was used by 44% of the units. Extracorporeal membrane oxygenation could be started in 44% of the units.
Ventilation treatment strategies for paediatric ARDS in the Nordic countries are relatively uniform and largely in accordance with international practice. The use of steroids and surfactant is more frequent than shown in other studies.
儿童急性呼吸窘迫综合征(ARDS)的治疗很大程度上基于从成人那里推断得来的知识,且不同医院之间存在差异。本研究探讨北欧国家儿童ARDS的通气治疗策略,并将其与国际实践进行比较。
2012年10月,向21家治疗儿童ARDS的北欧大型重症监护病房发送了一份关于1个月至6岁ARDS儿童通气治疗策略的问卷。排除早产儿和患有先天性疾病的儿童。
21家目标重症监护病房中有18家(86%)回复了问卷。其中50%的机构是儿科重症监护病房。44%的单位有书面指南。50%的单位经常使用带套囊的气管内导管。89%的单位通过压力控制实现通气,11%的单位通过容量控制实现通气。所有单位都使用支气管扩张剂,而使用类固醇的单位占83%,使用表面活性剂的单位占39%。94%的单位可使用吸入一氧化氮和高频振荡。44%的单位使用神经调节通气辅助。44%的单位可以启动体外膜肺氧合。
北欧国家儿童ARDS 的通气治疗策略相对统一,且很大程度上与国际实践一致。类固醇和表面活性剂的使用比其他研究显示的更为频繁。