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鼻旁窦神经鞘瘤的内镜切除术:10例患者的临床表现、治疗及结果

Endoscopic Resection of Sinonasal Tract Schwannoma: Presentation, Treatment, and Outcome in 10 Cases.

作者信息

Forer Boaz, Lin Leong Jern, Sethi Dharmbir Singh, Landsberg Roee

机构信息

Department of Otolaryngology-Head and Neck Surgery, Barzilai Medical Center, Ashkelon, Israel

Accent Ear Nose Throat Specialist Group, Mount Elizabeth Medical Centre, Singapore.

出版信息

Ann Otol Rhinol Laryngol. 2015 Aug;124(8):603-8. doi: 10.1177/0003489415572339. Epub 2015 Mar 11.

Abstract

BACKGROUND

Sinonasal schwannoma (SNS) is a rare sinonasal tract tumor whose presentation is similar to that of other benign nasal tumors. Very few case series appear in the literature. This study aims to describe the presentation, treatment, and outcome of 10 SNS cases from 3 referral centers.

METHODS

All SNS cases were analyzed retrospectively. Patient demographics, tumor data, surgical procedures, and outcome were recorded.

RESULTS

Five males and 5 females (mean age, 49.1 ± 21.4 years) were included in the study. The tumor was on the left side in 9 patients and on the right side in 1. It originated in the middle turbinate in 4 cases, the ethmoid and sphenoid sinuses in 2 cases, and the nasal septum and infratemporal fossa in 1 case each. Tumor resection was done endoscopically in all cases, and there was no need for an external procedure, and 5 patients did not require a sinusotomy. All 10 patients remained disease-free after a mean follow-up of 65.3 months (range, 2-120 months).

CONCLUSION

Safe and effective endoscopic resection of SNS is feasible. If the tumor is contained within the nasal cavity, simple tumor excision without sinusotomy can be enough to resect the tumor. In more extensive disease, a wider endoscopic approach may be needed, but an external approach was not necessary in this series.

摘要

背景

鼻窦神经鞘瘤(SNS)是一种罕见的鼻窦道肿瘤,其表现与其他良性鼻肿瘤相似。文献中出现的病例系列非常少。本研究旨在描述来自3个转诊中心的10例SNS病例的表现、治疗和结果。

方法

对所有SNS病例进行回顾性分析。记录患者人口统计学资料、肿瘤数据、手术过程和结果。

结果

本研究纳入5例男性和5例女性(平均年龄49.1±21.4岁)。9例患者肿瘤位于左侧,1例位于右侧。4例起源于中鼻甲,2例起源于筛窦和蝶窦,各有1例起源于鼻中隔和颞下窝。所有病例均通过内镜进行肿瘤切除,无需外部手术,5例患者无需进行鼻窦切开术。10例患者平均随访65.3个月(范围2 - 120个月)后均无疾病复发。

结论

SNS的安全有效内镜切除是可行的。如果肿瘤局限于鼻腔内,单纯肿瘤切除而不进行鼻窦切开术可能足以切除肿瘤。对于更广泛的病变,可能需要更广泛的内镜手术方法,但本系列病例中无需外部手术方法。

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