Melancia Diana, Abegão Pinto Luis, Marques-Neves Carlos
Department of Pharmacology and Neurosciences, Lisbon University, Lisbon, Portugal.
Ophthalmic Res. 2015;53(3):141-8. doi: 10.1159/000377635. Epub 2015 Mar 7.
Cataract surgery is one of the most performed surgeries in the developed world. In addition to its significant impact on visual acuity, phacoemulsification has been hailed as a potential intraocular pressure (IOP)-lowering procedure. While current evidence suggests an overall significant and sustained decrease in IOP to exist after cataract surgery, the specific ocular characteristics that could help predict which patients are likely to benefit from this IOP-lowering effect remain unclear. This definition is important in glaucoma patients if this surgery is to be used in the treatment for this disease. Our review aims to summarize the literature on the subject, depicting possible mechanisms behind this IOP decrease, which type of patients are more likely to benefit from this surgery for IOP-lowering purposes and ultimately help optimizing disease management for the increasing number of patients with concomitant glaucoma and cataract.
白内障手术是发达国家实施最多的手术之一。除了对视力有重大影响外，超声乳化术被誉为一种潜在的降低眼压（IOP）的手术。虽然目前的证据表明白内障手术后眼压总体上有显著且持续的下降，但有助于预测哪些患者可能从这种降低眼压的效果中获益的具体眼部特征仍不清楚。如果要将这种手术用于青光眼的治疗，这一定义对青光眼患者很重要。我们的综述旨在总结关于该主题的文献，描述眼压降低背后可能的机制，哪种类型的患者更有可能从这种降低眼压的手术中获益，并最终帮助优化对越来越多合并青光眼和白内障患者疾病的管理。
