Xiang W, Peng J, Song X, Xu A, Zhang D, Liu J, Bi Z
Department of Dermatology, The Third Hospital of Hangzhou, Hangzhou, China.
Department of Dermatology, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, China.
Skin Res Technol. 2016 Feb;22(1):32-9. doi: 10.1111/srt.12225. Epub 2015 Mar 12.
In vivo confocal laser scanning microscopy (CLSM) represents a promising technique for noninvasive visualization of lesions. Honeycomb pattern, cobblestone pattern, ringed pattern and dermal papillae are terms commonly used to describe CLSM architectures. Understanding of these four terms individually or in combination on confocal images facilitates the diagnosis and differential diagnosis of skin diseases.
Seventy-eight patients and 5 healthy controls were enrolled in the study. Their lesions were imaged with the VivaScope 1500 reflectance confocal microscope.
Concerning these four terms mentioned above, they had different features in different skin diseases and played an important role in the understanding of skin diseases individually or in combination.
By understanding the CLSM features of honeycomb pattern, cobblestone pattern, ringed pattern and dermal papillae individually or in combination, the findings support the roles of these characteristic architectures in diagnosis and differential diagnosis of skin diseases.
体内共聚焦激光扫描显微镜（CLSM）是一种用于病变无创可视化的有前景的技术。蜂巢状模式、鹅卵石样模式、环状模式和真皮乳头是常用于描述CLSM结构的术语。在共聚焦图像上单独或联合理解这四个术语有助于皮肤疾病的诊断和鉴别诊断。
本研究纳入了78例患者和5名健康对照。使用VivaScope 1500反射式共聚焦显微镜对他们的病变进行成像。
关于上述四个术语，它们在不同的皮肤疾病中具有不同的特征，单独或联合在皮肤疾病的理解中发挥着重要作用。
通过单独或联合理解蜂巢状模式、鹅卵石样模式、环状模式和真皮乳头的CLSM特征，这些发现支持了这些特征性结构在皮肤疾病诊断和鉴别诊断中的作用。
