Levenson Jessica C, Benca Ruth M, Rumble Meredith E
University of Pittsburgh School of Medicine, Pittsburgh, PA.
University of Wisconsin School of Medicine and Public Health, Madison, WI.
J Clin Sleep Med. 2015 Aug 15;11(8):847-54. doi: 10.5664/jcsm.4930.
Depression has been identified as the most common condition comorbid to insomnia, with findings pointing to the possibility that these disorders may be causally related to each other or may share common mechanisms. Some have suggested that comorbid insomnia and depression may have a different clinical course than either condition alone, and may thus require specific treatment procedures. In this report we examined the clinical characteristics of individuals referred to an academic sleep center who report comorbid symptoms of insomnia and depression and those with symptoms of insomnia outside the context of meaningful depression, and we identified differences between these groups with regard to several cognitive-related variables.
Logistic regression analyses examined whether past week worry, dysfunctional beliefs about sleep, and insomnia symptom-focused rumination predicted group membership.
Individuals with comorbid symptoms of insomnia and depression reported more past-week worry, dysfunctional beliefs about sleep, and insomnia symptom-focused rumination, than those with symptoms of insomnia without significant depression symptoms. When including all three cognitive-related variables in our model, those with comorbid symptoms reported more severe insomnia symptom-focused rumination, even when controlling for insomnia and mental health severity, among other relevant covariates.
The findings contribute to our understanding of the complex nature of comorbid symptoms of insomnia and depression and the specific symptom burden experienced by those with significant depression symptoms in the presence of insomnia. The findings also highlight the need for increased clinical attention to the sleep-focused rumination reported by these patients.
抑郁症已被确认为失眠最常见的共病状况,研究结果表明这些疾病可能存在因果关系,或者可能有共同的机制。一些人认为,共病的失眠和抑郁症可能具有与单独任何一种疾病不同的临床病程,因此可能需要特定的治疗程序。在本报告中,我们研究了转诊至一家学术睡眠中心、报告有失眠和抑郁症共病症状的个体以及那些在无明显抑郁症情况下有失眠症状的个体的临床特征,并确定了这些群体在几个认知相关变量方面的差异。
逻辑回归分析检验了过去一周的担忧、对睡眠的功能失调信念以及对失眠症状的反复思考是否能预测所属组别。
与无明显抑郁症状的失眠患者相比,有失眠和抑郁症共病症状的个体报告过去一周有更多担忧、对睡眠的功能失调信念以及对失眠症状的反复思考。当在我们的模型中纳入所有三个认知相关变量时,即使在控制了失眠和心理健康严重程度以及其他相关协变量的情况下,有共病症状的个体报告有更严重的对失眠症状的反复思考。
这些发现有助于我们理解失眠和抑郁症共病症状的复杂本质,以及在存在失眠的情况下有明显抑郁症状的个体所经历的特定症状负担。这些发现还凸显了临床需要更多关注这些患者报告的对睡眠的反复思考。