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饮食教育对 ADHD 的影响:一项随机对照临床试验。

The effect of dietary education on ADHD, a randomized controlled clinical trial.

机构信息

Research Center for Psychiatry and Behavioral Sciences, Department of Psychiatry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ; Department of Psychiatry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.

Research Center for Psychiatry and Behavioral Sciences, Department of Psychiatry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Ann Gen Psychiatry. 2015 Mar 1;14:12. doi: 10.1186/s12991-015-0050-6. eCollection 2015.

Abstract

BACKGROUND

The purpose of this research was to study the effectiveness of the overall dietary intervention rather than a single nutrient on children with attention deficit hyperactivity disorder (ADHD).

METHODS

This is a randomized controlled trial conducted at a child psychiatry clinic in Iran. Participants were 106 children and adolescents with ADHD. One group received methylphenidate plus dietary recommendations, while the other group only received methylphenidate. ADHD DSM-IV checklist was used to assess inattentiveness and hyperactivity/impulsivity scores at baseline and at the end of the trial.

RESULTS

The results revealed no significant difference between the two groups regarding mean age, gender ratio, body mass index, baseline inattentiveness score, and baseline hyperactivity score. Linear regression analysis considering the covariant variables showed that the inattentive score at the end of the trial was significantly associated with the mean change of favorite diet scores.

CONCLUSION

This is the first clinical trial examining the effect of overall dietary characteristics rather than a single nutrient on the children formally diagnosed with ADHD. According to the results, un-favorite diet had no effects on inattentive or hyperactivity/impulsivity score. Encouraging the children with ADHD to increase their intake of recommended diet markedly improves their attention.

TRIAL REGISTRATION

The trial was registered at the Iranian Clinical Trials Registry (Irct ID: IRCT201311303930N29).

摘要

背景

本研究旨在研究整体饮食干预而非单一营养素对注意缺陷多动障碍(ADHD)儿童的有效性。

方法

这是在伊朗一家儿童精神病诊所进行的随机对照试验。参与者为 106 名患有 ADHD 的儿童和青少年。一组接受哌醋甲酯加饮食建议,另一组仅接受哌醋甲酯。在基线和试验结束时使用 ADHD DSM-IV 清单评估注意力不集中和多动/冲动得分。

结果

两组在平均年龄、性别比例、体重指数、基线注意力不集中得分和基线多动得分方面无显著差异。考虑协变量的线性回归分析表明,试验结束时的注意力不集中得分与喜爱饮食评分的平均变化显著相关。

结论

这是首次临床试验,研究整体饮食特征而非单一营养素对正式诊断为 ADHD 的儿童的影响。根据结果,不喜爱的饮食对注意力不集中或多动/冲动得分没有影响。鼓励 ADHD 儿童增加推荐饮食的摄入量可显著改善他们的注意力。

试验注册

该试验在伊朗临床试验注册中心(Irct ID:IRCT201311303930N29)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2925/4357187/51a50e389c6f/12991_2015_50_Fig1_HTML.jpg

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