Long Liying, Peng Haiyan, Chen Xi, Wang Fei, Long Wenjie, Cheng Ming, Ma Jing
Department of Psychiatry, The School of Clinical Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Department of Psychiatry, Brain Hospital of Hunan Province (The Second People's Hospital of Hunan Province), Changsha, Hunan, 410007, People's Republic of China.
Neuropsychiatr Dis Treat. 2024 Mar 9;20:535-549. doi: 10.2147/NDT.S449186. eCollection 2024.
This study aimed to investigate the impact of implementing a low-lectin diet on gut microbiota composition and symptom amelioration in pediatric patients diagnosed with Attention Deficit Hyperactivity Disorder (ADHD).
A total of 58 children (ages 7-15 years), meeting the criteria for ADHD were recruited. In addition to standard medication treatment, participants in the experimental group with a low-lectin diet, while those in the control group received standard medication treatment alone. Clinical outcomes were assessed through evaluations conducted by physicians and teachers, implementation of the Conners Parent Rating Scales, and analysis of gut microbiota composition.
The results revealed significant improvements in symptom reduction and attention allocation rate within the experimental group, surpassing those observed in the control group. Specifically, the experimental group exhibited lower physician ratings, teacher ratings, and attention allocation rate compared to the control group. Moreover, analysis of gut microbiota composition identified notable distinctions between the two groups.
These findings provide compelling evidence and valuable guidance supporting the integration of a low-lectin diet as an adjunctive intervention for managing ADHD.
本研究旨在调查实施低凝集素饮食对被诊断为注意力缺陷多动障碍(ADHD)的儿科患者肠道微生物群组成及症状改善的影响。
共招募了58名符合ADHD标准的儿童(7至15岁)。除标准药物治疗外,实验组采用低凝集素饮食,而对照组仅接受标准药物治疗。通过医生和教师的评估、实施康纳斯父母评定量表以及分析肠道微生物群组成来评估临床结果。
结果显示,实验组在症状减轻和注意力分配率方面有显著改善,超过了对照组。具体而言,与对照组相比,实验组的医生评分、教师评分和注意力分配率更低。此外,对肠道微生物群组成的分析确定了两组之间的显著差异。
这些发现提供了有力的证据和有价值的指导,支持将低凝集素饮食作为治疗ADHD的辅助干预措施。