中风预防的进展。
Advances in stroke prevention.
作者信息
Sherzai Ayesha Z, Elkind Mitchell S V
机构信息
Departments of Neurology and Epidemiology, Columbia University Medical Center, New York, New York.
出版信息
Ann N Y Acad Sci. 2015 Mar;1338:1-15. doi: 10.1111/nyas.12723.
Abstract
Stroke remains to be a leading cause of disability. However, optimal strategies can prevent up to 80% of strokes. A large body of evidence supports many strategies for primary and secondary prevention of stroke. The purpose of this paper is to highlight recent major advances for management of modifiable medical and behavioral risk factors of stroke. Specific studies are highlighted, including those related to atrial fibrillation (AF), hypertension, revascularization, hyperlipidemia, antiplatelets, smoking, diet, and physical activity. Effective strategies include the use of novel oral anticoagulants for AF, antiplatelet therapy, and intensive lowering of atherosclerosis risk factors.
摘要
中风仍然是导致残疾的主要原因。然而，最佳策略可预防高达80%的中风。大量证据支持多种中风一级和二级预防策略。本文的目的是强调中风可改变的医学和行为风险因素管理方面的近期主要进展。重点介绍了具体研究，包括与心房颤动（AF）、高血压、血运重建、高脂血症、抗血小板治疗、吸烟、饮食和体育活动相关的研究。有效策略包括使用新型口服抗凝剂治疗AF、抗血小板治疗以及强化降低动脉粥样硬化风险因素。
相似文献
1
Advances in stroke prevention.中风预防的进展。
Ann N Y Acad Sci. 2015 Mar;1338:1-15. doi: 10.1111/nyas.12723.
2
The Proportion of Preventable Thrombectomy Procedures with Improved Atrial Fibrillation Stroke Prevention.可预防的取栓术比例与改善的房颤卒中预防。
J Stroke Cerebrovasc Dis. 2021 Apr;30(4):105599. doi: 10.1016/j.jstrokecerebrovasdis.2021.105599. Epub 2021 Feb 3.
3
New Avenues for Optimal Treatment of Atrial Fibrillation and Stroke Prevention.优化房颤治疗和卒中预防的新途径。
Stroke. 2021 Apr;52(4):1490-1499. doi: 10.1161/STROKEAHA.120.032060. Epub 2021 Feb 25.
4
Oral anticoagulants versus antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no history of stroke or transient ischemic attacks.口服抗凝剂与抗血小板治疗对预防非瓣膜性心房颤动且无卒中或短暂性脑缺血发作史患者卒中的疗效比较
Cochrane Database Syst Rev. 2007 Jul 18(3):CD006186. doi: 10.1002/14651858.CD006186.pub2.
5
Novel oral anticoagulants for stroke prevention in atrial fibrillation: focus on apixaban.新型口服抗凝药物在房颤卒中预防中的应用：重点关注阿哌沙班。
Adv Ther. 2012 Jun;29(6):491-507. doi: 10.1007/s12325-012-0026-8. Epub 2012 Jun 7.
6
European Primary Care Cardiovascular Society (EPCCS) consensus guidance on stroke prevention in atrial fibrillation (SPAF) in primary care.欧洲初级保健心血管学会（EPCCS）关于初级保健中房颤（AF）患者卒中预防（SPAF）的共识指南。
Eur J Prev Cardiol. 2016 Mar;23(5):460-73. doi: 10.1177/2047487315571890. Epub 2015 Feb 20.
7
Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines.当代抗血小板和抗凝治疗用于二级卒中预防：当前文献和指南的叙述性综述。
Curr Neurol Neurosci Rep. 2023 May;23(5):235-262. doi: 10.1007/s11910-023-01266-2. Epub 2023 Apr 11.
8
Atrial fibrillation and stroke: State-of-the-art and future directions.心房颤动与中风：现状与未来方向。
Curr Probl Cardiol. 2024 Jan;49(1 Pt C):102181. doi: 10.1016/j.cpcardiol.2023.102181. Epub 2023 Oct 31.
9
Epidemiology and Primary Prevention of Stroke.中风的流行病学与一级预防
Continuum (Minneap Minn). 2020 Apr;26(2):260-267. doi: 10.1212/CON.0000000000000831.
10
Anticoagulants or antiplatelet therapy for non-rheumatic atrial fibrillation and flutter.非风湿性心房颤动和心房扑动的抗凝或抗血小板治疗。
Cochrane Database Syst Rev. 2001(1):CD001938. doi: 10.1002/14651858.CD001938.
引用本文的文献
1
Machine learning algorithms to predict stroke in China based on causal inference of time series analysis.基于时间序列分析因果推断的中国脑卒中预测机器学习算法
BMC Neurol. 2025 May 31;25(1):236. doi: 10.1186/s12883-025-04261-x.
2
Reduced murine double minute-2 methylation from peripheral blood mononuclear cells correlates with enhanced oxidative stress in hepatitis b virus-related hepatocellular carcinoma.外周血单个核细胞中鼠双微体2甲基化水平降低与乙型肝炎病毒相关肝细胞癌中氧化应激增强相关。
Front Microbiol. 2025 May 13;16:1590492. doi: 10.3389/fmicb.2025.1590492. eCollection 2025.
3
Experiencing Cerebrovascular Diseases like Stroke and Fear of Falling: Longitudinal Results from the Survey of Health, Ageing and Retirement in Europe.经历过中风等脑血管疾病以及跌倒恐惧：来自欧洲健康、老龄化与退休调查的纵向结果
Geriatrics (Basel). 2024 Oct 11;9(5):133. doi: 10.3390/geriatrics9050133.
4
Association between glaucoma and stroke: A bidirectional mendelian randomization study.青光眼与中风之间的关联：一项双向孟德尔随机化研究。
Adv Ophthalmol Pract Res. 2024 Apr 23;4(3):147-155. doi: 10.1016/j.aopr.2024.04.003. eCollection 2024 Aug-Sep.
5
Assessment of Knowledge and attitude towards Stroke among the UAE population during the COVID-19 pandemic: A cross-sectional study.评估 COVID-19 大流行期间阿联酋人口对中风的认知和态度：一项横断面研究。
F1000Res. 2023 Oct 13;12:322. doi: 10.12688/f1000research.129873.2. eCollection 2023.
6
Voiding Dysfunction Due to Urethral Sphincter Dysfunction Might Be an Early Neurological Presentation of Central Nervous System Disorders in Aged Patients.由于尿道括约肌功能障碍导致的排尿功能障碍可能是老年患者中枢神经系统疾病的早期神经学表现。
J Pers Med. 2023 Apr 20;13(4):693. doi: 10.3390/jpm13040693.
7
Atherosclerotic Carotid Artery Disease: Where to from the emergency room? University hospital experience.动脉粥样硬化性颈动脉疾病：从急诊室出发？大学医院的经验。
Sultan Qaboos Univ Med J. 2022 Nov;22(4):561-565. doi: 10.18295/squmj.4.2022.028. Epub 2022 Nov 7.
8
Glutamate Scavenging as a Neuroreparative Strategy in Ischemic Stroke.谷氨酸清除作为缺血性中风的一种神经修复策略
Front Pharmacol. 2022 Mar 23;13:866738. doi: 10.3389/fphar.2022.866738. eCollection 2022.
9
Perceptions of recurrence risk and behavioural changes among first-ever and recurrent stroke survivors: A qualitative analysis.首次和复发性脑卒中幸存者对复发风险的认知和行为变化：一项定性分析。
Health Expect. 2021 Dec;24(6):1962-1970. doi: 10.1111/hex.13335. Epub 2021 Aug 6.
10
Evaluating the effects of socioeconomic status on stroke and bleeding risk scores and clinical events in patients on oral anticoagulant for new onset atrial fibrillation.评估社会经济地位对新发心房颤动患者口服抗凝剂后卒中及出血风险评分和临床事件的影响。
PLoS One. 2021 Mar 18;16(3):e0248134. doi: 10.1371/journal.pone.0248134. eCollection 2021.
本文引用的文献
1
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies.B型利钠肽和C反应蛋白在预测房颤风险中的作用：基于社区队列研究的CHARGE-AF联盟
Europace. 2014 Oct;16(10):1426-33. doi: 10.1093/europace/euu175. Epub 2014 Jul 18.
2
Cryptogenic stroke and underlying atrial fibrillation.隐匿性脑卒中与潜在的心房颤动。
N Engl J Med. 2014 Jun 26;370(26):2478-86. doi: 10.1056/NEJMoa1313600.
3
Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.《卒中和短暂性脑缺血发作患者卒中预防指南：美国心脏协会/美国卒中协会医疗保健专业人员指南》。
Stroke. 2014 Jul;45(7):2160-236. doi: 10.1161/STR.0000000000000024. Epub 2014 May 1.
4
C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study.C-反应蛋白作为腔隙性卒中后的预后标志物：卒中治疗中的炎症标志物水平研究。
Stroke. 2014 Mar;45(3):707-16. doi: 10.1161/STROKEAHA.113.004562. Epub 2014 Feb 12.
5
2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8).2014 年成人高血压管理的循证指南：第八届联合国家委员会（JNC 8）任命的专家组报告。
JAMA. 2014 Feb 5;311(5):507-20. doi: 10.1001/jama.2013.284427.
6
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.《2014年心脏病和中风统计数据更新：美国心脏协会报告》
Circulation. 2014 Jan 21;129(3):e28-e292. doi: 10.1161/01.cir.0000441139.02102.80. Epub 2013 Dec 18.
7
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.高风险颅内动脉狭窄患者（SAMMPRIS）强化药物治疗联合或不联合支架置入的疗效：一项随机试验的最终结果。
Lancet. 2014 Jan 25;383(9914):333-41. doi: 10.1016/S0140-6736(13)62038-3. Epub 2013 Oct 26.
8
New oral anticoagulants and the risk of intracranial hemorrhage: traditional and Bayesian meta-analysis and mixed treatment comparison of randomized trials of new oral anticoagulants in atrial fibrillation.新型口服抗凝剂与颅内出血风险：新型口服抗凝剂在心房颤动中随机试验的传统和贝叶斯荟萃分析和混合治疗比较。
JAMA Neurol. 2013 Dec;70(12):1486-90. doi: 10.1001/jamaneurol.2013.4021.
9
Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis.急性非心源性缺血性卒中和短暂性脑缺血发作的早期双联与单联抗血小板治疗：一项更新的系统评价和荟萃分析。
Circulation. 2013 Oct 8;128(15):1656-66. doi: 10.1161/CIRCULATIONAHA.113.003187. Epub 2013 Sep 12.
10
Dabigatran versus warfarin in patients with mechanical heart valves.达比加群酯与华法林用于机械心脏瓣膜患者的比较。
N Engl J Med. 2013 Sep 26;369(13):1206-14. doi: 10.1056/NEJMoa1300615. Epub 2013 Aug 31.
Zotero 插件