DiMartini Andrea F, Dew Mary Amanda, Butt Zeeshan, Simpson Mary Ann, Ladner Daniela P, Smith Abigail R, Hill-Callahan Peg, Gillespie Brenda W
Departments of Psychiatry, University of Pittsburgh, Pittsburgh, PA; Surgery, University of Pittsburgh, Pittsburgh, PA.
Liver Transpl. 2015 May;21(5):670-82. doi: 10.1002/lt.24108.
Although sexual functioning is an important facet of a living donor's quality of life, it has not received an extensive evaluation in this population. Using data from the Adult-to-Adult Living Donor Liver Transplantation Cohort Study, we examined donor sexual functioning across the donation process from the predonation evaluation to 3 months and 1 year after donation. Donors (n = 208) and a comparison group of nondonors (n = 155) completed self-reported surveys with specific questions on sexual desire, satisfaction, orgasm, and (for men) erectile function. Across the 3 time points, donor sexual functioning was lower at the evaluation phase and 3 months after donation versus 1 year after donation. In the early recovery period, abdominal pain was associated with difficulty reaching orgasm [odds ratio (OR), 3.98; 95% confidence interval (CI), 1.30-12.16], concerns over appearance were associated with lower sexual desire (OR, 4.14; 95% CI, 1.02-16.79), and not feeling back to normal was associated with dissatisfaction with sexual life (OR, 3.58; 95% CI, 1.43-8.99). Efforts to educate donors before the surgery and prepare them for the early recovery phase may improve recovery and reduce distress regarding sexual functioning.
尽管性功能是活体供者生活质量的一个重要方面，但在这一人群中尚未得到广泛评估。利用成人对成人活体供肝移植队列研究的数据，我们考察了供者在从捐献前评估到捐献后3个月及1年的整个捐献过程中的性功能情况。供者（n = 208）和一组非供者对照（n = 155）完成了自我报告调查，其中包含有关性欲、满意度、性高潮以及（男性的）勃起功能的特定问题。在这3个时间点中，与捐献后1年相比，供者在评估阶段和捐献后3个月时的性功能较低。在早期恢复阶段，腹痛与性高潮困难相关[比值比（OR），3.98；95%置信区间（CI），1.30 - 12.16]，对外表的担忧与性欲较低相关（OR，4.14；95%CI，1.02 - 16.79），感觉未恢复正常与对性生活不满意相关（OR，3.58；95%CI，1.43 - 8.99）。在手术前对供者进行教育并让他们为早期恢复阶段做好准备的措施，可能会改善恢复情况并减少性功能方面的困扰。
