Takahashi H, Nakazawa S, Shimura T
J Neurosurg. 1985 Jan;62(1):120-7. doi: 10.3171/jns.1985.62.1.0120.
Total excision is the treatment of choice in preventing the relapse of craniopharyngioma, but for tumors involving an extensive area, it is often associated with increased risks of complications. The efficacy of postoperative radiotherapy has not yet been established. The authors have performed minimal tumor excision followed by intensive injection of bleomycin into the remaining tumor as postoperative adjuvant therapy in seven children with craniopharyngioma. Long-term outcome in the children with cystic-type tumors containing little or no solid tissue has proven the regimen to be more advantageous than total excision.
全切除是预防颅咽管瘤复发的首选治疗方法，但对于累及范围广泛的肿瘤，往往会增加并发症的风险。术后放疗的疗效尚未得到证实。作者对7例颅咽管瘤患儿进行了肿瘤次全切除，随后向残留肿瘤内密集注射博来霉素作为术后辅助治疗。对于囊性肿瘤且几乎不含实性组织的患儿，长期结果证明该治疗方案比全切除更具优势。
