Dashtdar Mehrab, Dashtdar Mohammad Reza, Dashtdar Babak, Khan Saeed Ahmad
Department of Integrative Medicine, Dubai Pharmacy College, Dubai, United Arab Emirates.
Emergency Department, International Modern Hospital, Intensive Care Unit, Dubai, United Arab Emirates.
J Pharmacopuncture. 2013 Dec;16(4):14-21. doi: 10.3831/KPI.2013.16.026.
The objective of this study was to examine how an integrated approach to type 2 diabetes mellitus treatment could improve glycemic control and immune-potentiating activities adherent to oral hypoglycemic agents along with a botanical compound, among primary care patients.
In this study, we used the self-control and the group-control methods. Candidates meeting the trial conditions were selected from among volunteers who had taken the test substance for 45 days. During the trial, all groups were on a controlled diet; neither were the original medications nor their dosages changed.
The results showed that the botanical compound (Glyco-Persica(®)) significantly reduced the main clinical symptoms in diabetes type 2. In the treatment group, 36 of 52 patients (69.23%) and in the control group 10 of 52 patients (19.23%) showed reduced symptoms, and this difference was statistically significant (P< 0.05). The fasting blood sugar in the treatment group after treatment compared with that before treatment and with that in the control group after treatment was statistically different (P< 0.05). The post-prandial glucose in the treatment group after treatment was significantly different from that before treatment and from that in the control group after treatment (P< 0.05); the post-prandial blood sugar in the treatment group was reduced by 8.98%.
The results revealed that the botanical compound (Glyco-Persica(®)) has significant hypoglycemic properties which affect main clinical symptoms in diabetes type 2. Body weight, blood pressure, heart rate, routine blood, stool and urine tests showed no meaningful negative changes after the course of treatment. There was no significant adverse reaction during the trial.
本研究的目的是探讨在基层医疗患者中,采用综合方法治疗2型糖尿病如何改善血糖控制以及增强口服降糖药与一种植物化合物联合使用时的免疫增强活性。
在本研究中,我们采用了自身对照和组间对照方法。从服用受试物质45天的志愿者中挑选符合试验条件的受试者。在试验期间,所有组均采用控制饮食;原用药及剂量均未改变。
结果显示,植物化合物(Glyco-Persica(®))显著减轻了2型糖尿病的主要临床症状。治疗组52例患者中有36例(69.23%)症状减轻,对照组52例患者中有10例(19.23%)症状减轻,差异有统计学意义(P<0.05)。治疗组治疗后的空腹血糖与治疗前及对照组治疗后的空腹血糖相比,差异有统计学意义(P<0.05)。治疗组治疗后的餐后血糖与治疗前及对照组治疗后的餐后血糖相比,差异有统计学意义(P<0.05);治疗组餐后血糖降低了8.98%。
结果表明,植物化合物(Glyco-Persica(®))具有显著的降血糖特性,可影响2型糖尿病的主要临床症状。治疗过程结束后,体重、血压、心率、血常规、大便及尿常规检查均未出现有意义的负面变化。试验期间未出现明显不良反应。