Brady Kimberly L, Scott Glynis A, Gilmore Elaine S
Washington University.
Dermatol Online J. 2014 Dec 14;21(3):13030/qt2c8085xm.
Penile squamous cell carcinoma is a rare malignancy seen more frequently in developing nations. Metastasis occurs in a predictable manner, with superficial lymph node involvement occurring first, followed by deep lymph node involvement, and then distant spread. Brain, lung, liver, and bone are the typical sites of distant metastasis. We present the unusual case of an 81-year-old man with penile squamous cell carcinoma requiring total penectomy who developed a confluent red to violaceous, indurated suprapubic plaque with satellite papules and bulky inguinal lymphadenopathy. The shield-like clinical presentation and infiltrating strands and cords on histology resembled carcinoma en cuirasse, a rare form of cutaneous metastasis frequently associated with breast cancer but not reported with penile squamous cell carcinoma.
阴茎鳞状细胞癌是一种罕见的恶性肿瘤，在发展中国家更为常见。转移以可预测的方式发生，首先是浅表淋巴结受累，随后是深部淋巴结受累，然后是远处转移。脑、肺、肝和骨是远处转移的典型部位。我们报告了一例不寻常的病例，一名81岁患有阴茎鳞状细胞癌且需要行全阴茎切除术的男性，出现了融合性的红色至紫罗兰色、硬结性的耻骨上斑块，伴有卫星状丘疹和腹股沟淋巴结肿大。其盾牌样临床表现以及组织学上的浸润条索和索状结构类似于癌性铠甲，这是一种罕见的皮肤转移形式，常与乳腺癌相关，但未见与阴茎鳞状细胞癌相关的报道。
