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阴茎巨大鳞状细胞癌伴快速进展。

Giant squamous cell carcinoma of penis with rapid progression.

作者信息

Zhang Yongrui, Tian Runhui, Zhu Zhanmeng, Guo Kaimin

机构信息

Department of Urology, The First Hospital of Jilin University, Changchun, 130021, PR China.

Department of psychology, The first hospital of Jilin University, China.

出版信息

Urol Case Rep. 2020 Nov 19;34:101496. doi: 10.1016/j.eucr.2020.101496. eCollection 2021 Jan.

DOI:10.1016/j.eucr.2020.101496
PMID:33299798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7704335/
Abstract

A 65-year-old man presented with a giant ulcerative and malodorous genital mass rapidly growing for 5 months. On first presentation, he noticed a 3 cm × 2 cm cauliflower-like mass located in the penile dorsal shaft. But, he rejected any operation. Unfortunately, the lesion became aggressive and eventually destroyed the entire penile shaft and urethra within a five-month period. He underwent a radical penectomy, scrotal extended resection, formation of a perineal urethrostomy and left inguinal lymph node biopsy. Pathology revealed poor-differentiated invasive squamous cell carcinoma. The patient had an uneventful recovery.

摘要

一名65岁男性因巨大溃疡性且有恶臭的生殖器肿物就诊,该肿物迅速生长5个月。初诊时,他发现阴茎背侧有一个3厘米×2厘米的菜花状肿物。但他拒绝任何手术。不幸的是,病变进展迅速,最终在5个月内破坏了整个阴茎体和尿道。他接受了根治性阴茎切除术、阴囊扩大切除术、会阴尿道造口术及左侧腹股沟淋巴结活检。病理显示为低分化浸润性鳞状细胞癌。患者恢复顺利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/279711cfab93/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/eb19b45e3531/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/0cb8d23c93f7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/279711cfab93/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/eb19b45e3531/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/0cb8d23c93f7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf2/7704335/279711cfab93/gr3.jpg

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本文引用的文献

1
Cutaneous metastasis from penile squamous cell carcinoma resembling carcinoma en cuirasse.阴茎鳞状细胞癌的皮肤转移,类似铠甲状癌。
Dermatol Online J. 2014 Dec 14;21(3):13030/qt2c8085xm.
2
Giant squamous cell carcinoma of the penis.阴茎巨大鳞状细胞癌
Clin Exp Dermatol. 2010 Apr;35(3):e5-6. doi: 10.1111/j.1365-2230.2008.03156.x.
3
Penile cancer: epidemiology, pathogenesis and prevention.阴茎癌:流行病学、发病机制与预防
World J Urol. 2009 Apr;27(2):141-50. doi: 10.1007/s00345-008-0302-z. Epub 2008 Jul 8.
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Incidence trends in primary malignant penile cancer.原发性阴茎恶性肿瘤的发病率趋势
Urol Oncol. 2007 Sep-Oct;25(5):361-7. doi: 10.1016/j.urolonc.2006.08.029.