Estrovich Igor E, Shen Chris, Chu Yvonne, Downs J Crawford, Gardiner Stuart, Straiko Michael, Mansberger Steven L
Legacy Devers Eye Institute, Portland, OR.
Cornea. 2015 Jun;34(6):682-5. doi: 10.1097/ICO.0000000000000406.
To evaluate the location of the eye and tonometry device that provides the most accurate intraocular pressure (IOP) measurements in eyes with Boston type 1 keratoprosthesis.
A single surgeon sutured a Boston keratoprosthesis into the central cornea in the usual manner in 5 eyes of deceased donors. Another investigator used a 27-gauge needle, digital manometry, and gravity infusion to set the IOP at levels of 10, 20, 30, and 40 mm Hg in random order. A second investigator masked to the level of IOP used a Schiotz tonometer (Sklar) with a 7.5-g plunger load and a Tono-pen XL tonometer (Medtronic) to determine IOP at the temporal corneoscleral limbus and temporal sclera (3 mm temporal to the corneoscleral limbus). We used generalized estimation equation models to determine an average absolute difference between the tonometer measurements compared with the "gold standard" digital manometric IOP.
The Schiotz tonometer had a lower median absolute error compared with the Tono-pen at both temporal sclera (5.4 mm Hg vs. 39.0 mm Hg, P < 0.001) and corneoscleral limbus (4.9 vs. 15.0 mm Hg, P = 0.03). The median absolute error for Schiotz was similar at the temporal sclera and corneoscleral limbus (P = 0.44).
The Schiotz tonometer has the highest accuracy of IOP compared with the Tono-pen and gold standard digital manometry. Clinicians could consider Schiotz tonometry when measuring IOP in patients with keratoprosthesis.
评估在植入波士顿1型人工角膜的眼中,眼睛与眼压计的位置组合,哪种能提供最准确的眼内压(IOP)测量值。
一名外科医生以常规方式将波士顿人工角膜缝合到5只已故供体眼的中央角膜中。另一名研究人员使用27号针头、指压测压法和重力输注法,以随机顺序将眼压设定为10、20、30和40 mmHg。另一名对眼压水平不知情的研究人员使用配有7.5 g柱塞负载的Schiotz眼压计(Sklar)和Tono-pen XL眼压计(美敦力),在颞侧角膜缘和颞侧巩膜(角膜缘颞侧3 mm处)测量眼压。我们使用广义估计方程模型来确定眼压计测量值与“金标准”指压测压法测得的眼压之间的平均绝对差值。
在颞侧巩膜处(5.4 mmHg对39.0 mmHg,P < 0.001)和角膜缘处(4.9对15.0 mmHg,P = 0.03),Schiotz眼压计的中位绝对误差均低于Tono-pen眼压计。Schiotz眼压计在颞侧巩膜和角膜缘处的中位绝对误差相似(P = 0.44)。
与Tono-pen眼压计和金标准指压测压法相比,Schiotz眼压计测量眼压的准确性最高。临床医生在测量人工角膜植入患者的眼压时可考虑使用Schiotz眼压测量法。