体温升高对大鼠听神经-脑干诱发电位和脑电图的影响。

Effects of body temperature elevation on auditory nerve-brain-stem evoked responses and EEGs in rats.

作者信息

Gold S, Cahani M, Sohmer H, Horowitz M, Shahar A

出版信息

Electroencephalogr Clin Neurophysiol. 1985 Feb;60(2):146-53. doi: 10.1016/0013-4694(85)90021-5.

Abstract

ABRs and EEGs were recorded in anaesthetized rats during whole body hyperthermia. ABR amplitudes were decreased during warming, with little recovery as body temperature was lowered. The latencies of the ABR waves decreased with warming and increased with subsequent cooling. The major latency changes were in the later ABR waves. Warming was accompanied by suppression of the EEG. These results point out that ABR evaluation of patients must take into account elevated body temperatures. Since it has been shown that the rat can serve as a model of the effects of heat on man, an attempt is made to relate these ABR and EEG findings in rats to studies of human psychomotor performance during heat exposure.

摘要

在全身热疗过程中，对麻醉的大鼠记录听觉脑干反应（ABR）和脑电图（EEG）。升温过程中ABR波幅降低，体温降低时几乎没有恢复。ABR波的潜伏期随升温而缩短，随后降温时延长。主要的潜伏期变化发生在ABR波的后期。升温伴随着EEG的抑制。这些结果指出，对患者进行ABR评估时必须考虑体温升高的情况。由于已经表明大鼠可作为热对人类影响的模型，因此尝试将大鼠的这些ABR和EEG结果与热暴露期间人类心理运动表现的研究联系起来。