Hampel C, Neisius A, Thomas C, Thüroff J W, Roos F
Urologische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland,
Urologe A. 2015 Mar;54(3):349-58. doi: 10.1007/s00120-014-3679-x.
Vesicovaginal fistulae are much more common in developing countries along the equatorial fistula belt than in industrialized countries. However, although the classical obstetric fistula caused by lack of medical support through pregnancy and delivery in adolescent primiparae has almost vanished in Germany, we are now facing new and predominantly iatrogenic variants. Increasing frequency of gynecological surgery as well as pelvic radiation, forgotten vaginal foreign bodies, or uninhibited cancer growth are the modern causes for vesicovaginal fistula in elderly patients. Comorbidities and genital atrophy impair surgical therapy in view of a limited success rate of conservative transient transurethral catheterization.
Diagnostics should start early and should be initially limited to vaginal inspection, cystourethroscopy, and the blue dye test. Radiological investigations including CT and MRI are only indicated in patients suspicious for ureterovaginal fistula or with inconclusive findings or malignant fistula. The surgical armamentarium comprises vaginal, abdominal, and combined approaches, which all underlie basic principles of fistula repair: protection of the ureteral orifices, complete excision of the fistula canal, accurate separation of the organs connected to the fistula, sufficient tissue mobilization for tension-free suturing, interposition of padding material for prevention of recurrency.
Depending on the degree of sphincter damage, stress urinary incontinence might persist despite successful fistula repair, requiring further incontinence surgery or ultimate urinary diversion in recurrent cases that are hopeless.
膀胱阴道瘘在赤道瘘管带沿线的发展中国家比工业化国家更为常见。然而,尽管在德国,青春期初产妇因妊娠和分娩期间缺乏医疗支持而导致的经典产科瘘管几乎已消失,但我们现在正面临新的、主要是医源性的瘘管类型。妇科手术以及盆腔放疗频率的增加、遗忘的阴道异物或癌症的无节制生长是老年患者膀胱阴道瘘的现代病因。鉴于保守的经尿道临时插管成功率有限,合并症和生殖器萎缩会影响手术治疗效果。
诊断应尽早开始,最初应限于阴道检查、膀胱尿道镜检查和蓝色染料试验。包括CT和MRI在内的放射学检查仅适用于怀疑有输尿管阴道瘘或检查结果不明确或为恶性瘘管的患者。手术方法包括经阴道、经腹和联合手术,所有这些都遵循瘘管修复的基本原则:保护输尿管口、完整切除瘘管通道、准确分离与瘘管相连的器官、充分游离组织以进行无张力缝合、置入填充材料以防止复发。
根据括约肌损伤程度,尽管瘘管修复成功,压力性尿失禁仍可能持续存在,对于复发且无望的病例,需要进一步的尿失禁手术或最终进行尿流改道。