Rutkowski Tomasz W, Maciejewski Bogusław, Kołosza Zofia, Wygoda Andrzej, Składowski Krzysztof, Hejduk Beata, Rutkowski Roman
Department of Radiotherapy and Chemotherapy, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Poland.
Department of Radiotherapy, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Poland.
Contemp Oncol (Pozn). 2014;18(6):429-35. doi: 10.5114/wo.2014.44542. Epub 2014 Dec 31.
The retrospective chart review of 110 patients with T2 supraglottic cancer who underwent radiotherapy was performed to correlate tumor volume with other prognostic factors and to analyze its impact on treatment results. Patients with involved nodes, poor histopathological tumor differentiation, or hemoglobin concentration ≤ 14.3 g/dl had significantly larger tumors. Patients with large tumors had significantly lower 5-year local control rate, overall survival rate and presented significantly higher risk of nodal involvement and the ratio of poor histopathological differentiation of the tumor. Tumor volume significantly impacts radiotherapy outcome and should be considered to optimize treatment strategy for patients with T2 supraglottic cancer.
对110例接受放疗的T2期声门上癌患者进行回顾性病历审查，以将肿瘤体积与其他预后因素相关联，并分析其对治疗结果的影响。有淋巴结受累、组织病理学肿瘤分化差或血红蛋白浓度≤14.3 g/dl的患者肿瘤明显更大。肿瘤较大的患者5年局部控制率、总生存率明显较低，淋巴结受累风险和肿瘤组织病理学分化差的比例明显较高。肿瘤体积对放疗结果有显著影响，应考虑将其用于优化T2期声门上癌患者的治疗策略。
Zotero 插件