FM Kirby Neurobiology Center, Children's Hospital Boston, Boston, MA 02115, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
FM Kirby Neurobiology Center, Children's Hospital Boston, Boston, MA 02115, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Immunity. 2015 Mar 17;42(3):403-5. doi: 10.1016/j.immuni.2015.02.019.
Central nervous system trauma induces marked inflammation that has beneficial and deleterious consequences. In a recent issue of Neuron, Gadani et al. (2015) show that injured spinal cord releases the alarmin IL-33 to drive chemokines that recruit monocytes and promote recovery.
中枢神经系统创伤会引发明显的炎症,既有有益的后果,也有有害的后果。在《神经元》杂志的最近一期上,Gadani 等人(2015 年)表明,受伤的脊髓会释放警报素 IL-33,以驱动趋化因子募集单核细胞并促进恢复。