白细胞介素-33（IL-33）作为创伤性脑损伤的诊断和预后因素
Interleukin-33 (IL-33) as a Diagnostic and Prognostic Factor in Traumatic Brain Injury.
作者信息
Erenler Ali Kemal, Baydin Ahmet
机构信息
Hitit University, Faculty of Medicine, Department of Emergency Medicine, Çorum, Turkey.
Ondokuzmayıs University, Faculty of Medicine, Department of Emergency Medicine, Samsun, Turkey.
出版信息
Emerg Med Int. 2020 Jan 10;2020:1832345. doi: 10.1155/2020/1832345. eCollection 2020.
Abstract
Interleukin-33 (IL-33) is a cytokine involved in interleukin-1 family. Role of IL-33 in immune system activation is well described in the literature. IL-33 has been identified as an endogenous alarm signal (alarmin) to alert various types of immune cells to trauma. In this narrative review, we aimed to underline the diagnostic and prognostic importance of IL-33 in trauma, particularly in brain trauma.
摘要
白细胞介素-33（IL-33）是一种参与白细胞介素-1家族的细胞因子。IL-33在免疫系统激活中的作用在文献中已有充分描述。IL-33已被确定为一种内源性警报信号（警报素），可提醒各种免疫细胞注意创伤。在这篇叙述性综述中，我们旨在强调IL-33在创伤，特别是脑创伤中的诊断和预后重要性。
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