Division of Brain Sciences, Imperial College, Hammersmith Hospital, London, UK.
Centre for Clinical Pharmacology, University College London, London, UK.
Clin Pharmacol Ther. 2015 Aug;98(2):119-21. doi: 10.1002/cpt.120. Epub 2015 Jun 30.
Use of intravenous furosemide rather than oral administration in acute decompensated congestive cardiac failure is universally recommended in international guidelines. We argue that this recommendation is not supported by the existing evidence, and suggest that trials should be performed to determine whether larger doses of oral furosemide should be prescribed prior to an IV switch. This could reduce length of hospital admissions and allow for more patients to be managed in the primary care setting.
在国际指南中，普遍建议在急性失代偿性充血性心力衰竭中使用静脉注射呋塞米而非口服给药。我们认为，这一建议没有现有证据支持，并建议进行试验以确定在进行静脉注射转换之前是否应该开更大剂量的口服呋塞米。这可以缩短住院时间，并使更多患者能够在初级保健环境中得到管理。
