Lee C A, Fournier M J, Beckwith J
J Bacteriol. 1985 Mar;161(3):1156-61. doi: 10.1128/jb.161.3.1156-1161.1985.
The function of the stable 6S RNA of Escherichia coli is not known. Recently, it was proposed that the 6S RNA is a component of a bacterial signal recognition particle required for protein secretion. To test this proposal, we isolated a mutant that lacks the 6S RNA. Studies of the mutant show that the 6S RNA is not essential for growth or for protein secretion. The gene for the 6S RNA (ssr) maps near serA at 63 min on the E. coli genetic map.
大肠杆菌稳定的6S RNA的功能尚不清楚。最近,有人提出6S RNA是蛋白质分泌所需的细菌信号识别颗粒的一个组成部分。为了验证这一说法,我们分离出了一个缺乏6S RNA的突变体。对该突变体的研究表明,6S RNA对于生长或蛋白质分泌并非必不可少。6S RNA基因(ssr)在大肠杆菌遗传图谱上位于63分钟处,靠近serA。