Wang Audrey S, Wu Julie, Tuong William, Schupp Clayton, Armstrong April W
a Department of Dermatology , University of California, Davis , Sacramento , CA , USA .
b Cancer Prevention Institute of California , Fremont , CA , USA , and.
J Dermatolog Treat. 2015 Oct;26(5):435-9. doi: 10.3109/09546634.2015.1020915. Epub 2015 Mar 20.
We developed an Internet-based education tool (My Personalized Application for health Care Education, MyPACE) to promote patient comprehension about acne.
To determine if MyPACE improves clinical outcomes and quality of life in acne patients.
Modeling the spaced education approach, 50 participants received weekly multiple-choice questions for 12 weeks. Those randomized to the intervention group received acne-related questions, while those in the control group received non-dermatologic health-related questions. Acne lesion counts and Dermatology Life Quality Index (DLQI) scores were recorded at initial enrollment and at 12 weeks.
Within-group analysis for the intervention group showed a significant mean change in inflammatory and non-inflammatory acne lesions per person (-3.2 ± 1.3, p = 0.0219; -4.4 ± 1.8, p = 0.0267, respectively). The control group only demonstrated a significant mean change in inflammatory lesions (-2.8 ± 0.80, p = 0.0040). Both groups had statistically significant improvement in DLQI score. Compared with participants in the control group, those receiving acne-related questions experienced greater improvement in clinical outcomes and quality of life.
The small sample size limited our ability to detect statistically significant differences.
Internet-based, disease-specific, spaced education tools may be more effective than non-targeted tools for improving clinical outcomes and quality of life.
我们开发了一种基于互联网的教育工具(我的个性化医疗保健教育应用程序,MyPACE),以促进患者对痤疮的理解。
确定MyPACE是否能改善痤疮患者的临床结局和生活质量。
采用间隔教育方法进行建模,50名参与者在12周内每周收到多项选择题。随机分为干预组的参与者收到与痤疮相关的问题,而对照组的参与者收到与非皮肤病健康相关的问题。在初始入组时和12周时记录痤疮皮损计数和皮肤病生活质量指数(DLQI)评分。
干预组的组内分析显示,每人的炎性和非炎性痤疮皮损有显著的平均变化(分别为-3.2±1.3,p = 0.0219;-4.4±1.8,p = 0.0267)。对照组仅在炎性皮损方面有显著的平均变化(-2.8±0.80,p = 0.0040)。两组的DLQI评分均有统计学显著改善。与对照组的参与者相比,接受与痤疮相关问题的参与者在临床结局和生活质量方面有更大的改善。
样本量小限制了我们检测统计学显著差异的能力。
基于互联网的、针对特定疾病的间隔教育工具可能比非针对性工具在改善临床结局和生活质量方面更有效。