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无肠综合征:近乎全小肠切除术。

No gut syndrome: near total enterectomy.

作者信息

Huerta Sergio, Kukreja Sachin, Carter Kristen, Butler Dale

机构信息

University of Texas Southwestern Medical Center, Dallas, USA,

出版信息

J Gastrointest Surg. 2015 May;19(5):973-80. doi: 10.1007/s11605-015-2787-2. Epub 2015 Mar 20.

DOI:10.1007/s11605-015-2787-2
PMID:25791906
Abstract

In adult patients, removal of the entire jejunum and ileum (a near total enterectomy (NTE)) is considered a non-survivable event as patients undergoing this procedure might also suffer from an underlying illness that will lead to bowel necrosis such as septic or cardiac shock and respiratory failure. Parenteral nutrition (PN) dependency with its associated complications and quality of life issues further complicates management decisions in this group of patients. In the following report, we discuss our institutional experience with NTE and present a comprehensive review of the literature with patients undergoing NTE with the establishment of bowel continuity and successful outcomes even in cases dating as far back as the 1950s, over a decade prior to the implementation of PN. Review of the literature revealed 26 cases of NTE. Most of these patients are young (46.7 years old), and 57 % are women. These patients were reported to be alive at 21 months of follow-up. In this report, we present an individual 51 months following NTE. We also document the oldest patient receiving an NTE (76 years old). Both of these patients are alive on home PN. In cases where there is hemodynamic stability and patients request to continue with further care, the possibility of a NTE with bowel continuity and life-long PN might be entertained.

摘要

在成年患者中,切除整个空肠和回肠(近乎全小肠切除术(NTE))被认为是不可存活的事件,因为接受该手术的患者可能还患有潜在疾病,这将导致肠坏死,如感染性或心源性休克以及呼吸衰竭。肠外营养(PN)依赖及其相关并发症和生活质量问题使这组患者的管理决策更加复杂。在以下报告中,我们讨论了我们机构关于NTE的经验,并对文献进行了全面回顾,这些文献涉及接受NTE且建立了肠连续性并取得成功结果的患者,甚至包括可追溯到20世纪50年代的病例,即在PN实施前十多年。文献回顾发现了26例NTE病例。这些患者大多年轻(46.7岁),57%为女性。据报道,这些患者在随访21个月时仍存活。在本报告中,我们介绍了1例NTE术后51个月的患者。我们还记录了接受NTE的年龄最大的患者(76岁)。这两名患者均通过家庭PN维持生命。在血流动力学稳定且患者要求继续接受进一步治疗的情况下,可以考虑进行具有肠连续性和终身PN的NTE手术。

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Distal Duodenogastrostomy or Proximal Jejunogastrostomy in the Management of Ultra-Short Bowel.远端十二指肠胃吻合术或近端空肠胃吻合术在超短肠综合征中的应用。

本文引用的文献

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The current state of intestine transplantation: indications, techniques, outcomes and challenges.肠道移植的现状:适应证、技术、结果及挑战
Am J Transplant. 2014 Sep;14(9):1976-84. doi: 10.1111/ajt.12812. Epub 2014 Aug 6.
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Pathophysiology of short bowel syndrome: considerations of resected and residual anatomy.短肠综合征的病理生理学:对切除和残留解剖结构的考量
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Acute mesenteric ischemia.急性肠系膜缺血。
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More on 'No Gut Syndrome': A case report.关于“无肠道综合征”的更多内容:一则病例报告。
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Survival and dependence on home parenteral nutrition: experience over a 25-year period in a UK referral centre.家庭肠外营养的生存情况及依赖程度:英国一家转诊中心25年的经验
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A review of the quality of life of adult patients treated with long-term parenteral nutrition.长期接受肠外营养治疗的成年患者的生活质量综述。
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