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使用WEB-DL和WEB-SL对宽颈前交通动脉瘤进行血管内治疗:多中心研究的短期结果

Endovascular treatment of wide-neck anterior communicating artery aneurysms using WEB-DL and WEB-SL: short-term results in a multicenter study.

作者信息

Gherasim D N, Gory B, Sivan-Hoffmann R, Pierot L, Raoult H, Gauvrit J-Y, Desal H, Barreau X, Herbreteau D, Riva R, Ambesi Impiombato F, Armoiry X, Turjman F

机构信息

From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.).

From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.)

出版信息

AJNR Am J Neuroradiol. 2015 Jun;36(6):1150-4. doi: 10.3174/ajnr.A4282. Epub 2015 Mar 19.

Abstract

BACKGROUND AND PURPOSE

Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.

MATERIALS AND METHODS

Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.

RESULTS

Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.

CONCLUSIONS

In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.

摘要

背景与目的

宽颈前交通动脉瘤的血管内治疗通常具有挑战性。编织型血管内桥接(WEB)装置是一种最近开发的用于颅内动脉瘤血管内治疗的瘤内血流干扰装置。本研究的目的是探讨WEB双层和WEB单层装置治疗宽颈前交通动脉瘤的可行性、安全性和有效性。

材料与方法

分析了2013年6月至2014年3月期间在5个法国中心接受WEB装置治疗的前交通动脉瘤患者。分析手术成功率、技术并发症、1个月时的临床结局以及即刻和3至6个月的血管造影随访结果。

结果

10例未破裂的前交通动脉瘤患者,平均瘤颈直径为5.4mm,接受了WEB治疗。10个动脉瘤中有3个治疗失败,未出现进一步的临床并发症。1例患者发生了手术相关的血栓栓塞事件,其他6例在1个月随访时神经学检查结果正常。即刻解剖学结局评估显示,7例患者中有6例闭塞充分(完全闭塞或瘤颈残留)。所有患者均获得了血管造影控制,包括短期随访时6例动脉瘤闭塞充分(3例完全闭塞和3例瘤颈残留)。

结论

在我们的小样本系列研究中,使用WEB装置治疗宽颈前交通动脉瘤是可行且安全的。然而,由于WEB装置导航的局限性,基于动脉瘤和母动脉的初始血管造影表现进行患者选择很重要

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