格雷夫斯病中的广泛性上睑缘角膜结膜炎：病例报告及文献综述
Extensive superior limbic keratoconjunctivitis in Graves' disease: case report and mini-review of the literature.
作者信息
Chelala Elias, El Rami Hala, Dirani Ali, Fakhoury Henry, Fadlallah Ali
机构信息
Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
出版信息
Clin Ophthalmol. 2015 Mar 10;9:467-8. doi: 10.2147/OPTH.S79561. eCollection 2015.
BACKGROUND
Superior limbic keratoconjunctivitis (SLK) is characterized as an inflammation of the superior bulbar conjunctiva with predominant involvement of the superior limbus and adjacent epithelial keratitis.
METHODS
A 51-year-old woman, with a history of medically controlled Graves' disease was seen with an extensive SLK involving 5 mm of the superior cornea.
RESULTS
Total remission was observed with topical steroids (DXM). Recurrence was observed 1 week after steroid discontinuation, and steroidal treatment was reintroduced with tapering over 1 month. Total remission was then observed for 1 year.
CONCLUSION
Extensive keratitis and vascular pannus in SLK is rarely reported. This form could be treated with topical steroids. Tapering treatment remains essential for long-term success.
背景
上睑缘角结膜炎（SLK）的特征是上睑球结膜炎症，主要累及上角膜缘和相邻的上皮性角膜炎。
方法
一名51岁女性，有药物控制的格雷夫斯病病史，因广泛的SLK累及上方角膜5mm前来就诊。
结果
局部使用类固醇（地塞米松）后观察到完全缓解。停用类固醇1周后观察到复发，随后重新引入类固醇治疗并在1个月内逐渐减量。然后观察到完全缓解持续1年。
结论
SLK中广泛的角膜炎和血管翳很少见。这种类型可以用局部类固醇治疗。逐渐减量治疗对于长期成功仍然至关重要。
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