固定对比目鱼肌和腓肠肌胶原蛋白溶解度的影响：对大鼠比目鱼肌和腓肠肌胶原蛋白的生化研究。
Effect of immobilization on solubility of soleus and gastrocnemius muscle collagen: -biochemical studies on collagen from soleus and gastrocnemius muscles of rat.
作者信息
Sugama S, Tachino K, Haida N
机构信息
Department of Rehabilitation, Anamizu General Hospital, Ishikawa-ken 927-0027.
Department of Physical Therapy, Kanazawa University, Faculty of Medicine, School of Health Sciences, Kanazawa 920-0942, Japan.
出版信息
J Jpn Phys Ther Assoc. 1999;2(1):25-9. doi: 10.1298/jjpta.2.25.
We have been studying mainly the changes in collagen fiber solubility with respect to its influence on immobilization of the soleus muscle and Achilles tendon of rats. We decided to investigate also the change of the collagen fiber solubility in the gastrocnemius muscle which, like the soleus muscle, is assumed to influence the range of motion of the ankle joints. The purpose of this study, therefore, was to investigate the effects of a 7-week immobilization on the solubility of the gastrocnemius muscle and soleus muscle collagen fiber of rats. The results were that in a 7-week immobilization period, hydroxyproline concentration in tissue was increased and salt and pepsin soluble collagen was decreased in both the soleus and the gastrocnemius muscles. The results suggest an increase in the collagen concentration in tissue and an increase in the intermolecular cross-link with a stronger molecular structure. As far as the amount of collagen and solubility were concerned, the immobilization had a similar influence on the collagen fiber in both muscles.
我们主要研究了胶原纤维溶解度的变化及其对大鼠比目鱼肌和跟腱固定的影响。我们还决定研究腓肠肌中胶原纤维溶解度的变化，因为与比目鱼肌一样，腓肠肌被认为会影响踝关节的活动范围。因此，本研究的目的是探讨7周固定对大鼠腓肠肌和比目鱼肌胶原纤维溶解度的影响。结果显示，在7周的固定期内，比目鱼肌和腓肠肌组织中的羟脯氨酸浓度增加，盐溶性和胃蛋白酶溶性胶原减少。结果表明组织中胶原浓度增加，分子间交联增加，分子结构更强。就胶原含量和溶解度而言，固定对两块肌肉中的胶原纤维有相似的影响。
Zotero 插件