Trachtenberg Barry H, Cordero-Reyes Andrea, Elias Barbara, Loebe Matthias
Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas.
Methodist Debakey Cardiovasc J. 2015 Jan-Mar;11(1):28-32. doi: 10.14797/mdcj-11-1-28.
Since the advent of ventricular assist devices with smaller configurations and continuous-flow technology, survival rates for patients with end-stage heart failure have dramatically improved. While the burden of infectious complications is decreased in patients on continuous-flow ventricular assist devices compared to bulkier pulsatile-flow devices, infection remains one of the most common causes of morbidity and mortality. The majority of infections occur at the driveline exit site, beginning with a disruption or trauma to the barrier between the skin and driveline and sometimes spreading deeper. Once infections develop, they can be difficult to eradicate. Depending on the degree of infection, treatment options may include local wound care, antibiotics, or surgical treatment. Preventive strategies and careful surveillance are crucial to improve patient outcomes.
自从出现了配置更小且采用连续血流技术的心室辅助装置以来，终末期心力衰竭患者的生存率有了显著提高。与体积更大的搏动血流装置相比，使用连续血流心室辅助装置的患者感染并发症负担有所减轻，但感染仍然是发病和死亡的最常见原因之一。大多数感染发生在驱动线出口部位，始于皮肤与驱动线之间屏障的破坏或创伤，有时会扩散至更深部位。一旦感染发生，就可能难以根除。根据感染程度，治疗选择可能包括局部伤口护理、使用抗生素或手术治疗。预防策略和仔细监测对于改善患者预后至关重要。
