Nasri Hamid, Rafieian-Kopaei Mahmoud
Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan.
Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Iran J Pediatr. 2014 Oct;24(5):565-8. Epub 2014 Sep 12.
Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects.
二甲双胍是一种双胍类口服抗糖尿病药物，是治疗2型糖尿病患者高血糖的常用处方药。二甲双胍有三种不同作用，包括血糖调节作用、作为有效抗氧化剂保护肾小管细胞以及最终通过挽救足细胞对糖尿病肾病产生改善作用。因此，糖尿病患者可能从这三种不同的改善作用中均获益。
