Singh Sukhchain, Sethi Ankur, Singh Mukesh, Khosla Sandeep
aDepartment of Hospital Medicine at Ingalls Memorial Hospital, Harvey bDepartment of Cardiovascular Medicine at Mount Sinai Hospital Medical Center cDepartment of Cardiovascular Medicine at Rosalind Franklin University of Medicine and Science, Chicago, Illinois, USA.
Blood Press Monit. 2015 Aug;20(4):178-85. doi: 10.1097/MBP.0000000000000115.
Prevalence of interarm systolic blood pressure difference and clinical and demographic characteristics associated with interarm systolic blood pressure difference (IASBPD) have been a matter of debate. We aimed to ascertain the prevalence of IASBPD and clinical and demographic characteristics associated with it. We searched PubMed, EMBASE, and CINAHL, Ovid and Cochrane Library, and Google Scholar. Twenty-seven studies meeting all inclusion criteria were included in the analysis. Weighted average cumulative prevalence of simultaneous IASBPD of 10, 15, and 20 mmHg or greater was 9.49% [95% confidence interval (CI) 7.9-11.1%], 5.3% (95% CI 3.1-7.5%), and 4.4% (95% CI 1.5-7.4%), respectively. The prevalence of IASBPD of 10 mmHg was 9% (95% CI 7-11%), 7.5% (95% CI 5.6-9.4%), and 12.1% (95% CI 8.2-16.1%) in outpatient, community, and hospital-based setting, respectively. The prevalence of IASBPD of 15 mmHg was 4.9% (95% CI 2.7-7.2%) in outpatient and 8% in hospital setting. The prevalence of IASBPD of 20 mmHg was 4.4% (95% CI 2.8-11.6%) in outpatient and 4.4% (95% CI 2.1-6.8%) for the hospital setting. Pairwise meta-analysis of five studies showed that the presence or absence of IASBP was not associated with age, sex, diabetes, hypertension, dyslipidemia, and smoking history. However, participants with IASBPD of 10 mmHg or greater had a higher BMI compared with those with IASBPD of less than 10 mmHg. After BMI, hypertension and dyslipidemia had strongest association with IASBPD, but results were not statistically significant. IASBPD is relatively prevalent, but prevalence is lower than that previously reported. Prevalence is higher when blood pressure is measured in hospital setting compared with outpatient and community setting.
双臂收缩压差值的患病率以及与双臂收缩压差值（IASBPD）相关的临床和人口统计学特征一直存在争议。我们旨在确定IASBPD的患病率及其相关的临床和人口统计学特征。我们检索了PubMed、EMBASE、CINAHL、Ovid、Cochrane图书馆和谷歌学术。27项符合所有纳入标准的数据纳入分析。同时出现10、15和20 mmHg及以上的IASBPD加权平均累积患病率分别为9.49%[95%置信区间（CI）7.9 - 11.1%]、5.3%（95% CI 3.1 - 7.5%）和4.4%（95% CI 1.5 - 7.4%）。在门诊、社区和医院环境中，10 mmHg的IASBPD患病率分别为9%（95% CI 7 - 11%）、7.5%（95% CI 5.6 - 9.4%）和12.1%（95% CI 8.2 - 16.1%）。在门诊环境中，15 mmHg的IASBPD患病率为4.9%（95% CI 2.7 - 7.2%），在医院环境中为8%。在门诊环境中，20 mmHg的IASBPD患病率为4.4%（95% CI 2.8 - 11.6%），在医院环境中为4.4%（95% CI 2.1 - 6.8%）。五项研究的成对荟萃分析表明，IASBP的存在与否与年龄、性别、糖尿病、高血压、血脂异常和吸烟史无关。然而，与IASBPD小于10 mmHg的参与者相比，IASBPD为10 mmHg及以上的参与者BMI更高。除BMI外，高血压和血脂异常与IASBPD的关联最强，但结果无统计学意义。IASBPD相对普遍，但患病率低于先前报道。与门诊和社区环境相比，在医院环境中测量血压时患病率更高。
