Wächter Miriam, Pfeffer Martin, Schulz Nicole, Balling Anneliese, Chirek Aleksandra, Bach Jan-Peter, Moritz Andreas, Kohn Barbara, Pachnicke Stefan, Silaghi Cornelia
1 Comparative Tropical Medicine and Parasitology, Ludwig-Maximilians-Universität München , Munich, Germany .
Vector Borne Zoonotic Dis. 2015 Mar;15(3):191-4. doi: 10.1089/vbz.2014.1715.
Tick-transmitted spotted fever group Rickettsiae (SFGR) are considered emerging disease pathogens in Europe. To assess the situation in Germany, a seroepidemiologic survey of dogs (n=605, which have never left Germany) was conducted to determine the prevalence of antibodies to SFGR. For this purpose, a commercially available enzyme-linked immunosorbent assay (ELISA) test for all SFGR was used. A total of 78% of the dogs were positive for antibodies of the SFGR, and there was a positive correlation between age, tick-infestation, and seropositivity. There was no correlation between clinical state, location, and seropositivity, suggesting that infection with rickettsia is neither related to the health condition of the dogs nor to their abode in Germany. According to our results, all of Germany can be considered as an endemic area for SFGR. This should be taken into account when assessing the epidemiology of human rickettsioses and their impact on public health.
蜱传播的斑点热群立克次体（SFGR）被认为是欧洲的新兴疾病病原体。为评估德国的情况，对从未离开过德国的605只狗进行了血清流行病学调查，以确定抗SFGR抗体的流行率。为此，使用了一种针对所有SFGR的市售酶联免疫吸附测定（ELISA）检测。共有78%的狗SFGR抗体呈阳性，年龄、蜱虫感染与血清阳性之间存在正相关。临床状态、地点与血清阳性之间无相关性，这表明立克次体感染既与狗的健康状况无关，也与它们在德国的居住地无关。根据我们的结果，整个德国都可被视为SFGR的地方性流行区。在评估人类立克次体病的流行病学及其对公共卫生的影响时，应考虑到这一点。
