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[胰腺癌的放射治疗——文献综述]

[Radiotherapy of pancreas cancer--literature review].

作者信息

Roth S, Sack H, Thesen N, Mödder U

出版信息

Radiologe. 1985 Jan;25(1):41-7.

PMID:2579412
Abstract

Resection is the treatment of choice in organ-limited pancreatic cancer. In locally or regional, not completely resectable pancreatic cancer other therapeutic modalities are called upon: external beam radiotherapy results in relief of pain in 50% and average survival rate of about 10 months according to recent series in the literature. Loco-regional tumor control can be improved by intraoperative electrons or interstitial implantation of radioactive sources. - The combination of monochemotherapy (5-fluorouracil) and 40 Gy radiotherapy is well tolerated and tends to prolong survival also if given after curative resection.

摘要

手术切除是局限性胰腺癌的首选治疗方法。对于局部或区域的、无法完全切除的胰腺癌,则需采用其他治疗方式:根据近期文献报道,外照射放疗可使50%的患者疼痛缓解,平均生存期约为10个月。术中电子放疗或放射性源的组织间植入可改善局部区域肿瘤控制。单药化疗(5-氟尿嘧啶)与40 Gy放疗联合应用耐受性良好,即使在根治性切除术后应用也有延长生存期的趋势。

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