22-氧代胆甾烷作为植物生长促进剂。

22-Oxocholestanes as plant growth promoters.

作者信息

Zeferino-Diaz Reyna, Hilario-Martinez J Ciciolil, Rodriguez-Acosta Maricela, Sandoval-Ramirez Jesus, Fernandez-Herrera Maria A

机构信息

Facultad de Ciencias Quimicas, Benemerita Universidad Autonoma de Puebla, Ciudad Universitaria, 72570 Puebla, Pue., Mexico.

Escuela de Biologia-Licenciatura Multidisciplinaria en Biotecnologia, Benemerita Universidad Autonoma de Puebla, Ciudad Universitaria, 72570 Puebla, Pue., Mexico; Herbario y Jardin Botanico, Benemerita Universidad Autonoma de Puebla, Ciudad Universitaria, 72570 Puebla, Pue., Mexico.

出版信息

Steroids. 2015 Jun;98:126-31. doi: 10.1016/j.steroids.2015.03.005. Epub 2015 Mar 18.

DOI:10.1016/j.steroids.2015.03.005

PMID:25795152

Abstract

The spirostanic steroidal side-chain of diosgenin and hecogenin was modified to produce 22-oxocholestane derivatives. This type of side-chain was obtained in good yields through a straightforward four-step pathway. These compounds show potent brassinosteroid-like growth promoting activity evaluated via the rice lamina joint inclination bioassay. This is the first report of steroidal skeletons bearing the 22-oxocholestane side-chain and preserving the basic structure (A-D rings) from their corresponding parent compounds acting as plant growth promoters.

摘要

将薯蓣皂苷元和海柯皂苷元的螺甾烷甾体侧链进行修饰，以制备22-氧代胆甾烷衍生物。通过一条直接的四步路线可高产率地获得这类侧链。通过水稻叶片夹角生物测定法评估，这些化合物显示出强效的油菜素内酯样促生长活性。这是关于带有22-氧代胆甾烷侧链且保留其相应母体化合物的基本结构（A-D环）的甾体骨架作为植物生长促进剂的首次报道。