Liu Xuefeng, Rodriguez Carlos J, Wang Kesheng
Department of Systems Leadership and Effectiveness Science, University of Michigan, Ann Arbor, MI, USA.
Division of Public Health Sciences, Department of Epidemiology, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Internal Medicine (Cardiology), Wake Forest School of Medicine, Winston-Salem, NC, USA.
J Am Soc Hypertens. 2015 Mar;9(3):197-205. doi: 10.1016/j.jash.2015.01.002. Epub 2015 Jan 13.
The prevalence and long-term trends of isolated systolic hypertension (ISH) among untreated adults have not been reported. Data from 24,653 participants aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999-2010. The prevalence and 95% confidence intervals (CIs) of untreated ISH were estimated by conducting the independent survey t-test. The prevalence of untreated ISH was 9.4% and decreased from 10.3% in 1999-2004 to 8.5% in 2005-2010 (P = .00248). Old persons, females, and non-Hispanic blacks had higher prevalence of untreated ISH. Compared with 1999-2004, the prevalence of untreated ISH in 2005-2010 decreased among older (33.6%; 95% CI, 30.9%-36.3% vs. 25.1%; 95% CI, 22.7%-27.5%) and female individuals (8.3%; 95% CI, 7.5-9.2% vs. 11.4%; 95% CI, 10.4-12.3%). The stratified prevalence of untreated ISH declined in 2005-2010 (vs. 1999-2004) for older non-Hispanic whites (24.6% vs. 32.8%; P < .0001) and blacks (27.7% vs. 40.8%; P = .0013), non-Hispanic white females (7.5% vs. 10.8%; P < .0001), older individuals with higher education (21.0% vs. 30.6%; P = .0024), and females with lower education (10.1% vs. 13.1%; P = .006). Untreated ISH is more prevalent in older adults and females. Significant decreases in untreated ISH prevalence over time among these groups suggest that public health measures and/or treatment patterns are trending in the right direction.
未经治疗的成年人中单纯收缩期高血压（ISH）的患病率及长期趋势尚无报道。从1999 - 2010年国家健康与营养检查调查中选取了24,653名年龄≥18岁的参与者的数据。通过进行独立样本t检验来估计未经治疗的ISH的患病率及95%置信区间（CI）。未经治疗的ISH患病率为9.4%，从1999 - 2004年的10.3%降至2005 - 2010年的8.5%（P = 0.00248）。老年人、女性和非西班牙裔黑人未经治疗的ISH患病率较高。与1999 - 2004年相比，2005 - 2010年老年人（33.6%；95% CI，30.9% - 36.3% 对比 25.1%；95% CI，22.7% - 27.5%）和女性（8.3%；95% CI，7.5 - 9.2% 对比 11.4%；95% CI，10.4 - 12.3%）中未经治疗的ISH患病率有所下降。2005 - 2010年（对比1999 - 2004年），老年非西班牙裔白人（24.6% 对比 32.8%；P < 0.0001）、黑人（27.7% 对比 40.8%；P = 0.0013）、非西班牙裔白人女性（7.5% 对比 10.8%；P < 0.0001）、受过高等教育的老年人（21.0% 对比 30.6%；P = 0.0024）以及受教育程度较低的女性（10.1% 对比 13.1%；P = 0.006）中未经治疗的ISH分层患病率均有所下降。未经治疗的ISH在老年人和女性中更为普遍。这些群体中未经治疗的ISH患病率随时间显著下降，表明公共卫生措施和/或治疗模式正朝着正确方向发展。
