Kopchak O O, Bachyns'ka N Iu, Kholin V O
Wiad Lek. 2014;67(2 Pt 2):202-6.
To analyze the characteristics of cognitive impairment (CI) in patients of different age with dyscirculatory encephalopathy (DE) and metabolic syndrome (MS). There were 503 patients aged 45-89 years with DE enrolled into the study, who were divided into two groups: patients without MS (n = 198) and with MS (n = 305). All patients were divided into three subgroups depending on age. In patients with MS more severe CI was diagnosed, compared with patients without MS. The negative impact of MS on the state of cognitive function was found mainly in patients of middle and old age, while in elderly patients we did not find significant influence of MS on cognitive decline. In patients with DE MS influenced more significantly on executive cognitive functions.
分析不同年龄的循环障碍性脑病(DE)和代谢综合征(MS)患者认知障碍(CI)的特征。本研究纳入了503例年龄在45 - 89岁的DE患者,将其分为两组:无MS患者(n = 198)和有MS患者(n = 305)。所有患者根据年龄分为三个亚组。与无MS患者相比,MS患者被诊断出更严重的CI。MS对认知功能状态的负面影响主要见于中老年患者,而在老年患者中未发现MS对认知衰退有显著影响。在DE患者中,MS对执行认知功能的影响更为显著。