Hromnats'ka N M
Wiad Lek. 2014;67(2 Pt 2):306-10.
To study dyslipidemia types in children with metabolic syndrome.
From 1520 children of total population 155 children aged from 9 to 18 years were selected, who formed 2 groups: 1 group--85 children with metabolic syndrome, 2 group--54 children with normal body mass. Anthropometry, blood pressure measurement, estimation of total cholesterol, low density cholesterol, very low density cholesterol, high density cholesterol, tryglicerides in blood were done.
The total cholesterol level was 1,1 times higher (p = 0.001), low density cholesterol 1,4 times higher (p = 0.001), very low density cholesterol 1,1 times higher (p= 0.015), tryglicerides 1,1 times higher (p = 0.020) in children with metabolic syndrome than in children of control group. In children with metabolic syndrome sensitively more often IIa, IV dislipidemia types and isolated hypercholesterolemia and less often IIb, III dislipidemia types and high density cholesterol isolated decrease were diagnosed. So children with metabolic syndrome were characterized by atherogenic types of dislipidemias which determine early atherosclerosis development. Children with metabolic syndrome must be examined on the lipid metabolism violation with the aim of its prevention and correction.
研究代谢综合征患儿的血脂异常类型。
从1520名儿童的总体人群中选取155名9至18岁的儿童，分为2组：1组——85名患有代谢综合征的儿童，2组——54名体重正常的儿童。进行人体测量、血压测量、血液中总胆固醇、低密度胆固醇、极低密度胆固醇、高密度胆固醇、甘油三酯的测定。
代谢综合征患儿的总胆固醇水平比对照组儿童高1.1倍（p = 0.001），低密度胆固醇高1.4倍（p = 0.001），极低密度胆固醇高1.1倍（p = 0.015），甘油三酯高1.1倍（p = 0.020）。在代谢综合征患儿中，更常检测出IIa型、IV型血脂异常以及单纯高胆固醇血症，而较少检测出IIb型、III型血脂异常以及单纯高密度胆固醇降低。因此，代谢综合征患儿的特征是具有致动脉粥样硬化的血脂异常类型，这决定了早期动脉粥样硬化的发展。必须对代谢综合征患儿进行脂质代谢紊乱检查，以预防和纠正这种情况。
