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氨氯地平和比索洛尔在高血压患者中的应用

[Amlodipine and bisoprolol application in patients with arterial hypertension].

作者信息

Zaremba Ie Kh, Zaremba-Fedchyshyn O V, Virna M M, Bula M S, Zaremba O V

出版信息

Wiad Lek. 2014;67(2 Pt 2):326-7.

Abstract

SUMMARY The paper represents the changes in the daily monitoring of blood pressure with combined drug alotendyn (bisoprolol and amlodipine). We had examined 28 patients with arterial hypertension stage II, II degree with poorly controlled blood pressure. Alotendynadministered at the dose of 5/5 (1 tablet twice daily) for 10-14 days. The study demonstrated the effectiveness of a fixed-dose combination of bisoprolol and amlodipine in patients with hypertension represented by the decrease of average SBP, DBP, heart rate, increase in the number of patients with a normal daily profile ("dipper"), decrease in the time index. The lack of adverse effects, high efficiency, good tolerance increases patients compliance to the treatment.

摘要

摘要 本文介绍了联合用药阿洛替尼(比索洛尔和氨氯地平)在每日血压监测中的变化情况。我们对28例II期、II级动脉高血压且血压控制不佳的患者进行了研究。阿洛替尼以5/5的剂量(每日两次,每次1片)给药,持续10 - 14天。研究表明,比索洛尔和氨氯地平的固定剂量组合对高血压患者有效,表现为平均收缩压、舒张压、心率降低,日常血压模式正常(“勺型”)的患者数量增加,时间指数降低。缺乏不良反应、高效、耐受性好提高了患者对治疗的依从性。

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