甲硝唑中毒表现为急性失语和右侧肢体无力。

Metronidazole toxicity presenting with acute onset of aphasia and right sided weakness.

作者信息

Demel Stacie L, Jovin Tudor G, Jadhav Ashutosh P

机构信息

Department of Neurology, University of Pittsburgh Medical Center, Kaufmann Medical Building Suite 811, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA.

出版信息

J Clin Neurosci. 2015 Jul;22(7):1199-200. doi: 10.1016/j.jocn.2014.12.018. Epub 2015 Mar 18.

DOI:10.1016/j.jocn.2014.12.018

PMID:25796956

Abstract

We report a 37-year-old man with a history of cirrhosis and methicillin-sensitive staphylococcus aureus (MSSA) bacteremia who presented from a nursing home with 1 week of progressive confusion followed by acute onset of aphasia, forced left eye deviation and right sided weakness. While clinical presentation was concerning for a left middle cerebral artery stroke, MRI was consistent with leukoencephalopathy. The man had been on metronidazole for 2 months for treatment of Clostridium difficile infection. This case exemplifies a stroke mimic to be considered when a patient presents with an acute focal neurological deficit.

摘要

我们报告了一名37岁男性，有肝硬化和甲氧西林敏感金黄色葡萄球菌（MSSA）菌血症病史，从疗养院送来，有1周进行性意识模糊，随后急性失语、左眼强迫性偏斜和右侧无力。虽然临床表现令人担忧左大脑中动脉卒中，但磁共振成像（MRI）结果与白质脑病一致。该男子因艰难梭菌感染接受甲硝唑治疗2个月。此病例例证了在患者出现急性局灶性神经功能缺损时需考虑的一种类卒中情况。