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机器人辅助腹腔镜前列腺切除术中保留膀胱颈后的控尿结果。

Continence outcomes after bladder neck preservation during robot-assisted laparoscopic prostatectomy (RALP).

作者信息

Gu Xiao, Araki Motoo, Wong Carson

机构信息

a 1 Department of Urology, University of Oklahoma Health Sciences Center , Oklahoma City, OK, USA.

b 2 Department of Urology, Clinical Medical College at Yangzhou University , Yangzhou, Jiangsu, China.

出版信息

Minim Invasive Ther Allied Technol. 2015;24(6):364-71. doi: 10.3109/13645706.2015.1027711. Epub 2015 Mar 22.

Abstract

PURPOSE

Urinary incontinence is one of the major prostate cancer treatment-related morbidities. We review our initial robot-assisted laparoscopic prostatectomy (RALP) experience, focusing on post-surgery continence rates.

MATERIAL AND METHODS

Two-hundred and thirty-three consecutive patients were identified from a prospectively maintained RALP database. A bladder neck sparing dissection was preferentially performed during transperitoneal RALP. On postoperative day 5 or 6 (clinic logistics), the urethral catheter was removed following a normal cystogram.

RESULTS

Median operative time was 190 minutes and estimated blood loss was 75 mL. Three (1.3%) patients required bladder neck reconstruction, while 198 (85.0%) had bilateral, 20 (8.6%) had unilateral and 15 (6.4%) did not undergo nerve sparing prostatectomy. One-hundred and ninety-nine (85.4%) patients had negative surgical margins. Median hospitalization and urethral catheter duration were 1.0 and 5.0 days, respectively. At six weeks, a median 1.0 pad per day usage was reported and mean AUASS and QoL were significantly improved from baseline (p < 0.05). Of the 220 patients having a minimum three-month follow-up, 152 (69.1%) achieved urinary continence without pads. Age, AUASS, QoL, prostate volume and prior TUR surgery independently had significant impact on early continence rate (p < 0.05).

CONCLUSION

A bladder neck sparing dissection allows for early return of urinary continence following RALP without compromising cancer control.

摘要

目的

尿失禁是前列腺癌治疗相关的主要并发症之一。我们回顾了我们最初的机器人辅助腹腔镜前列腺切除术(RALP)经验,重点关注术后控尿率。

材料与方法

从一个前瞻性维护的RALP数据库中识别出233例连续患者。在经腹RALP过程中优先进行膀胱颈保留性解剖。术后第5天或第6天(临床安排),在膀胱造影正常后拔除尿道导管。

结果

中位手术时间为190分钟,估计失血量为75毫升。3例(1.3%)患者需要进行膀胱颈重建,198例(85.0%)进行了双侧、20例(8.6%)进行了单侧以及15例(6.4%)未进行保留神经的前列腺切除术。199例(85.4%)患者手术切缘阴性。中位住院时间和尿道导管留置时间分别为1.0天和5.0天。六周时,报告的中位每日使用尿垫数为1.0个,平均AUASS和生活质量较基线显著改善(p<0.05)。在220例至少随访三个月的患者中,152例(69.1%)实现了无尿垫的尿控。年龄、AUASS、生活质量、前列腺体积和既往TUR手术对早期控尿率有独立的显著影响(p<0.05)。

结论

膀胱颈保留性解剖可使RALP术后尿控功能早日恢复,且不影响癌症控制。

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