Stein D J, Koen N, Donald K A, Adnams C M, Koopowitz S, Lund C, Marais A, Myers B, Roos A, Sorsdahl K, Stern M, Tomlinson M, van der Westhuizen C, Vythilingum B, Myer L, Barnett W, Brittain K, Zar H J
Department of Psychiatry and Mental Health, University of Cape Town, South Africa; Medical Research Council (MRC), Unit on Anxiety & Stress Disorders, South Africa.
Department of Psychiatry and Mental Health, University of Cape Town, South Africa; Medical Research Council (MRC), Unit on Anxiety & Stress Disorders, South Africa.
J Neurosci Methods. 2015 Aug 30;252:27-35. doi: 10.1016/j.jneumeth.2015.03.016. Epub 2015 Mar 19.
Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms that impact on child health, but there is a paucity of birth cohort data from low and middle-income countries (LMIC). We describe the rationale for and present baseline findings from the psychosocial component of the Drakenstein Child Health Study (DCHS).
We review the psychosocial measures used in the DCHS, a multidisciplinary birth cohort study in a peri-urban area in South Africa, and provide initial data on psychological distress, depression, substance use, and exposure to traumatic stressors and intimate partner violence (IPV). These and other measures will be assessed longitudinally in mothers in order to investigate associations with child neurodevelopmental and health outcomes.
Baseline psychosocial data is presented for mothers (n=634) and fathers (n=75) who have completed antenatal assessments to date. The sample of pregnant mothers is characterized by multiple psychosocial risk factors, including a high prevalence of psychological distress and depression, high levels of substance use, and high exposure to traumatic stressors and IPV.
These data are consistent with prior South African studies which have documented a high prevalence of a multitude of risk factors during pregnancy. Further longitudinal assessment of mothers and children may clarify the underlying psychobiological and psychosocial mechanisms which impact on child health, and so inform clinical and public health interventions appropriate to the South African and other LMIC contexts.
生命早期的心理生物学和社会心理因素在影响儿童健康结果方面起着关键作用。纵向研究可能有助于阐明相关的风险和复原力概况,以及影响儿童健康的潜在机制,但低收入和中等收入国家(LMIC)的出生队列数据匮乏。我们描述了德拉肯斯坦儿童健康研究(DCHS)社会心理部分的基本原理,并展示了基线研究结果。
我们回顾了DCHS中使用的社会心理测量方法,这是一项在南非城郊地区进行的多学科出生队列研究,并提供了关于心理困扰、抑郁、物质使用以及接触创伤性应激源和亲密伴侣暴力(IPV)的初始数据。这些及其他测量方法将在母亲中进行纵向评估,以调查与儿童神经发育和健康结果的关联。
呈现了迄今为止完成产前评估的母亲(n = 634)和父亲(n = 75)的基线社会心理数据。怀孕母亲样本的特点是存在多种社会心理风险因素,包括心理困扰和抑郁的高患病率、高水平的物质使用以及高暴露于创伤性应激源和IPV。
这些数据与南非先前的研究一致,那些研究记录了孕期多种风险因素的高患病率。对母亲和儿童进行进一步的纵向评估可能会阐明影响儿童健康的潜在心理生物学和社会心理机制,从而为适合南非和其他低收入和中等收入国家情况的临床和公共卫生干预提供依据。