Suppr超能文献

探究非洲儿童健康的社会心理决定因素:德拉肯斯泰因儿童健康研究。

Investigating the psychosocial determinants of child health in Africa: The Drakenstein Child Health Study.

作者信息

Stein D J, Koen N, Donald K A, Adnams C M, Koopowitz S, Lund C, Marais A, Myers B, Roos A, Sorsdahl K, Stern M, Tomlinson M, van der Westhuizen C, Vythilingum B, Myer L, Barnett W, Brittain K, Zar H J

机构信息

Department of Psychiatry and Mental Health, University of Cape Town, South Africa; Medical Research Council (MRC), Unit on Anxiety & Stress Disorders, South Africa.

Department of Psychiatry and Mental Health, University of Cape Town, South Africa; Medical Research Council (MRC), Unit on Anxiety & Stress Disorders, South Africa.

出版信息

J Neurosci Methods. 2015 Aug 30;252:27-35. doi: 10.1016/j.jneumeth.2015.03.016. Epub 2015 Mar 19.

Abstract

BACKGROUND

Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms that impact on child health, but there is a paucity of birth cohort data from low and middle-income countries (LMIC). We describe the rationale for and present baseline findings from the psychosocial component of the Drakenstein Child Health Study (DCHS).

METHODS

We review the psychosocial measures used in the DCHS, a multidisciplinary birth cohort study in a peri-urban area in South Africa, and provide initial data on psychological distress, depression, substance use, and exposure to traumatic stressors and intimate partner violence (IPV). These and other measures will be assessed longitudinally in mothers in order to investigate associations with child neurodevelopmental and health outcomes.

RESULTS

Baseline psychosocial data is presented for mothers (n=634) and fathers (n=75) who have completed antenatal assessments to date. The sample of pregnant mothers is characterized by multiple psychosocial risk factors, including a high prevalence of psychological distress and depression, high levels of substance use, and high exposure to traumatic stressors and IPV.

DISCUSSION

These data are consistent with prior South African studies which have documented a high prevalence of a multitude of risk factors during pregnancy. Further longitudinal assessment of mothers and children may clarify the underlying psychobiological and psychosocial mechanisms which impact on child health, and so inform clinical and public health interventions appropriate to the South African and other LMIC contexts.

摘要

背景

生命早期的心理生物学和社会心理因素在影响儿童健康结果方面起着关键作用。纵向研究可能有助于阐明相关的风险和复原力概况,以及影响儿童健康的潜在机制,但低收入和中等收入国家(LMIC)的出生队列数据匮乏。我们描述了德拉肯斯坦儿童健康研究(DCHS)社会心理部分的基本原理,并展示了基线研究结果。

方法

我们回顾了DCHS中使用的社会心理测量方法,这是一项在南非城郊地区进行的多学科出生队列研究,并提供了关于心理困扰、抑郁、物质使用以及接触创伤性应激源和亲密伴侣暴力(IPV)的初始数据。这些及其他测量方法将在母亲中进行纵向评估,以调查与儿童神经发育和健康结果的关联。

结果

呈现了迄今为止完成产前评估的母亲(n = 634)和父亲(n = 75)的基线社会心理数据。怀孕母亲样本的特点是存在多种社会心理风险因素,包括心理困扰和抑郁的高患病率、高水平的物质使用以及高暴露于创伤性应激源和IPV。

讨论

这些数据与南非先前的研究一致,那些研究记录了孕期多种风险因素的高患病率。对母亲和儿童进行进一步的纵向评估可能会阐明影响儿童健康的潜在心理生物学和社会心理机制,从而为适合南非和其他低收入和中等收入国家情况的临床和公共卫生干预提供依据。

相似文献

1
Investigating the psychosocial determinants of child health in Africa: The Drakenstein Child Health Study.
J Neurosci Methods. 2015 Aug 30;252:27-35. doi: 10.1016/j.jneumeth.2015.03.016. Epub 2015 Mar 19.
2
Intimate partner violence: associations with low infant birthweight in a South African birth cohort.
Metab Brain Dis. 2014 Jun;29(2):281-99. doi: 10.1007/s11011-014-9525-4. Epub 2014 Apr 12.
3
Maternal psychosocial risk factors and lower respiratory tract infection (LRTI) during infancy in a South African birth cohort.
PLoS One. 2019 Dec 30;14(12):e0226144. doi: 10.1371/journal.pone.0226144. eCollection 2019.
5
Early childhood wheezing phenotypes and determinants in a South African birth cohort: longitudinal analysis of the Drakenstein Child Health Study.
Lancet Child Adolesc Health. 2023 Feb;7(2):127-135. doi: 10.1016/S2352-4642(22)00304-2. Epub 2022 Nov 23.
6
Associations between maternal mental health and early child wheezing in a South African birth cohort.
Pediatr Pulmonol. 2018 Jun;53(6):741-754. doi: 10.1002/ppul.24008. Epub 2018 Apr 10.
7
Risk Factors for Antenatal Depression and Associations with Infant Birth Outcomes: Results From a South African Birth Cohort Study.
Paediatr Perinat Epidemiol. 2015 Nov;29(6):505-14. doi: 10.1111/ppe.12216. Epub 2015 Aug 3.
10
Effect of Hazardous Alcohol Use During Pregnancy on Growth Outcomes at Birth: Findings from a South African Cohort Study.
Alcohol Clin Exp Res. 2018 Feb;42(2):369-377. doi: 10.1111/acer.13566. Epub 2017 Dec 28.

引用本文的文献

1
Screening young children for neurodevelopmental differences in sub-Saharan Africa: a scoping review.
BMC Psychiatry. 2025 Sep 15;25(1):857. doi: 10.1186/s12888-025-07279-0.
3
Associations of maternal alcohol and non-prescribed substance use with early child growth.
S Afr J Psychiatr. 2025 Jun 12;31:2486. doi: 10.4102/sajpsychiatry.v31i0.2486. eCollection 2025.
5
Cell type-specific methylome-wide association studies of childhood ADHD symptoms.
medRxiv. 2025 Apr 17:2025.04.16.25325956. doi: 10.1101/2025.04.16.25325956.
9
Prenatal alcohol exposure alters brain structure and neurocognitive outcomes for 6- to 7-year-old children in a South African birth cohort.
Alcohol Clin Exp Res (Hoboken). 2025 May;49(5):1028-1041. doi: 10.1111/acer.70048. Epub 2025 Apr 6.

本文引用的文献

1
Race, ethnicity, and socioeconomic status in research on child health.
Pediatrics. 2015 Jan;135(1):e225-37. doi: 10.1542/peds.2014-3109.
2
Investigating the early-life determinants of illness in Africa: the Drakenstein Child Health Study.
Thorax. 2015 Jun;70(6):592-4. doi: 10.1136/thoraxjnl-2014-206242. Epub 2014 Sep 16.
7
Early lung development: lifelong effect on respiratory health and disease.
Lancet Respir Med. 2013 Nov;1(9):728-42. doi: 10.1016/S2213-2600(13)70118-8. Epub 2013 Aug 13.
8
Persistent effects of maternal smoking during pregnancy on lung function and asthma in adolescents.
Am J Respir Crit Care Med. 2014 Feb 15;189(4):401-7. doi: 10.1164/rccm.201302-0323OC.
9
Factor structure of the Beck Depression Inventory-II among South Africans receiving antiretroviral therapy.
AIDS Care. 2014 Feb;26(2):257-62. doi: 10.1080/09540121.2013.802278. Epub 2013 Jun 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验