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心脏黏液瘤的当前诊断与管理

Current diagnosis and management of cardiac myxomas.

作者信息

Jain Sonia, Maleszewski Joseph J, Stephenson Christopher R, Klarich Kyle W

机构信息

Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.

出版信息

Expert Rev Cardiovasc Ther. 2015 Apr;13(4):369-75. doi: 10.1586/14779072.2015.1024108.

Abstract

Cardiac myxoma is the most common cardiac neoplasm. In the majority of cases, it is isolated (non-syndromic) and located in the left atrium. In up to 10% cases, it is seen in syndromic association with the Carney complex where it is encountered in younger patients, with atypical and multiple locations, such as the right atrium or ventricles, and carries a high risk of recurrence. Imaging is pivotal in the diagnosis, management guidance and surveillance. Surgical excision is the established definitive treatment. Further research should address management strategies in incidentally discovered small myxomas in asymptomatic patients and the role of genetic testing and screening in syndromic myxomas.

摘要

心脏黏液瘤是最常见的心脏肿瘤。在大多数情况下,它是孤立性的(非综合征性),位于左心房。高达10%的病例中,它与卡尼综合征相关联,在年轻患者中出现,位置不典型且多发,如右心房或心室,复发风险高。影像学在诊断、管理指导和监测中起着关键作用。手术切除是既定的确定性治疗方法。进一步的研究应关注无症状患者偶然发现的小黏液瘤的管理策略以及基因检测和筛查在综合征性黏液瘤中的作用。

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