1. Anatomy Department, Center for Interdisciplinary Research Egas Moniz, Health Sciences Institute, Monte de Caparica, Portugal;
2. Pathology Department, Hospital Santa Maria, Lisboa, Portugal;
Int J Med Sci. 2015 Feb 27;12(3):264-9. doi: 10.7150/ijms.11309. eCollection 2015.
Tooth wear is a complex multifactorial process that involves the loss of hard dental tissue. Parafunctional habits have been mentioned as a self-destructive process caused by stress, which results in hyperactivity of masticatory muscles. Stress manifests itself through teeth grinding, leading to progressive teeth wear. The effects of continuous exposure to industrial noise, a "stressor" agent, cannot be ignored and its effects on the teeth must be evaluated.
The aim of this study was to ascertain the effects of industrial noise on dental wear over time, by identifying and quantifying crown area loss.
39 Wistar rats were used. Thirty rats were divided in 3 experimental groups of 10 animals each. Animals were exposed to industrial noise, rich in LFN components, for 1, 4 and 7 months, with an average weekly exposure of 40 hours (8h/day, 5 days/week with the weekends in silence). The remaining 9 animals were kept in silence. The areas of the three main cusps of the molars were measured under light microscopy.
A two-way ANOVA model was applied at significance level of 5%.
The average area of the molar cusps was significantly different between exposed and non-exposed animals. The most remarkable differences occurred between month 1 and 4. The total crown loss from month 1 to month 7 was 17.3% in the control group, and 46.5% in the exposed group, and the differences between these variations were significant (p<0.001).
Our data suggest that industrial noise is an important factor in the pathogenesis of tooth wear.
本研究旨在通过确定和量化牙冠面积损失来确定工业噪声对牙齿磨损的长期影响。
使用了 39 只 Wistar 大鼠。将 30 只大鼠分为 3 个实验组，每组 10 只。动物暴露于富含 LFN 成分的工业噪声中 1、4 和 7 个月，平均每周暴露 40 小时（每天 8 小时，每周 5 天，周末安静）。其余 9 只动物保持安静。在光镜下测量磨牙三个主要尖的面积。
在 5%的显著性水平上应用了双因素方差分析模型。
暴露组和未暴露组动物的磨牙牙尖平均面积有显著差异。最显著的差异发生在第 1 个月和第 4 个月之间。从第 1 个月到第 7 个月，对照组的总牙冠损失为 17.3%，而暴露组为 46.5%，这些变化之间的差异具有统计学意义（p<0.001）。
我们的数据表明，工业噪声是牙齿磨损发病机制中的一个重要因素。
