Cavacas Maria Alzira, Doroteia Carolina, Leonardo Ana Margarida, Proença Luís, Tavares Vítor
Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Almada, Portugal.
Anatomy Department, Instituto Universitário Egas Moniz, Almada, Portugal.
Front Oral Health. 2022 Sep 15;3:859664. doi: 10.3389/froh.2022.859664. eCollection 2022.
Morphological changes induced by industrial noise have been experimentally observed in several organs. This study aims to characterize the effect of industrial noise on the pulp cell density of Wistar rats from a histological point of view, through qualitative and quantitative analysis. The histologic sections were observed over the optical microscope and photographed using 10x and 40x magnifications and analyzed using an image processing software. They refer to a group of animals exposed to industrial noise for 3 months and for 7 months (EG) and another group of animals kept in silence for control (CG) during the same periods. There was a significant decrease in pulp cell density in teeth of the animals exposed for 3 months when compared to control teeth group ( = 0.01). However, in the group exposed for 7 months, no statistically significant differences were found ( = 0.66). Even so, we found an evident relationship between exposure to industrial noise and teeth morphological changes. The observed changes are similar to the modifications found on aged teeth. Therefore, this study places industrial noise as an aggressive stimulus that can cause a reaction of the pulp-dentin complex with morphological changes compatible with premature aging of the tooth.
在多个器官中通过实验观察到了工业噪声引起的形态学变化。本研究旨在从组织学角度，通过定性和定量分析，描述工业噪声对Wistar大鼠牙髓细胞密度的影响。在光学显微镜下观察组织学切片，使用10倍和40倍放大倍数进行拍照，并使用图像处理软件进行分析。它们涉及一组在3个月和7个月内暴露于工业噪声的动物（实验组），以及另一组在同一时期保持安静作为对照的动物（对照组）。与对照牙齿组相比，暴露3个月的动物牙齿中的牙髓细胞密度显著降低（P = 0.01）。然而，在暴露7个月的组中，未发现统计学上的显著差异（P = 0.66）。即便如此，我们发现工业噪声暴露与牙齿形态变化之间存在明显关系。观察到的变化与老年牙齿中发现的变化相似。因此，本研究将工业噪声视为一种侵袭性刺激，可导致牙髓 - 牙本质复合体发生反应，出现与牙齿过早老化相符的形态变化。
