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Ca(2+) and Ca(2+)-interlocked membrane guanylate cyclase signal modulation of neuronal and cardiovascular signal transduction.

作者信息

Sharma Rameshwar K, Baehr Wolfgang, Makino Clint L, Duda Teresa

机构信息

Research Divisions of Biochemistry and Molecular Biology, The Unit of Regulatory and Molecular Biology, Salus University Elkins Park, PA, USA.

School of Medicine, Department of Ophthalmology and Visual Sciences, University of Utah Salt Lake City, UT, USA.

出版信息

Front Mol Neurosci. 2015 Mar 6;8:7. doi: 10.3389/fnmol.2015.00007. eCollection 2015.

DOI:10.3389/fnmol.2015.00007
PMID:25798085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4351612/
Abstract
摘要

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Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes phosphoinositide hydrolysis, Ca(2+) release, and activation of protein kinase C.鸟苷酸环化酶/利钠肽受体-A 信号通路拮抗磷酸肌醇水解、钙离子释放和蛋白激酶 C 的激活。
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Membrane guanylate cyclase, a multimodal transduction machine: history, present, and future directions.膜鸟苷酸环化酶，一种多模式转导机器：历史、现状与未来方向。
Front Mol Neurosci. 2014 Jul 2;7:56. doi: 10.3389/fnmol.2014.00056. eCollection 2014.
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PDE9A is expressed in the inner retina and contributes to the normal shape of the photopic ERG waveform.PDE9A 在视网膜内层表达，并有助于光 ERG 波形的正常形态。
Front Mol Neurosci. 2014 Jun 27;7:60. doi: 10.3389/fnmol.2014.00060. eCollection 2014.
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Membrane guanylyl cyclase complexes shape the photoresponses of retinal rods and cones.膜鸟苷酸环化酶复合物塑造视网膜视杆细胞和视锥细胞的光反应。
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