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Proteostasis collapse, inter-tissue communication, and the regulation of aging at the organismal level.

作者信息

Dubnikov Tatyana, Cohen Ehud

机构信息

Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel - Canada, The Hebrew University School of Medicine Jerusalem, Israel.

出版信息

Front Genet. 2015 Mar 5;6:80. doi: 10.3389/fgene.2015.00080. eCollection 2015.

DOI:10.3389/fgene.2015.00080
PMID:25798145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4350417/
Abstract
摘要

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本文引用的文献

1
Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans.线虫秀丽隐杆线虫中神经元nhl-1对热休克因子1和DAF-16的差异调节。
Cell Rep. 2014 Dec 24;9(6):2192-205. doi: 10.1016/j.celrep.2014.11.028. Epub 2014 Dec 11.
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Proteostasis and longevity: when does aging really begin?蛋白质稳态与长寿:衰老究竟何时开始?
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XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity.XBP-1 是一种细胞非自主性应激抗性和寿命的调节因子。
Cell. 2013 Jun 20;153(7):1435-47. doi: 10.1016/j.cell.2013.05.042.
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Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood.生殖干细胞停滞在秀丽隐杆线虫成年早期抑制体细胞蛋白质稳态的崩溃。
Aging Cell. 2013 Oct;12(5):814-22. doi: 10.1111/acel.12110. Epub 2013 Jun 28.
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A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans.一种神经元 GPCR 对于线虫 C. elegans 中热休克反应的诱导至关重要。
J Neurosci. 2013 Apr 3;33(14):6102-11. doi: 10.1523/JNEUROSCI.4023-12.2013.
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Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.线虫中 FOXO 蛋白对基因的直接和间接调控:GATA 因子和脂质基因调控因子的作用。
Cell Metab. 2013 Jan 8;17(1):85-100. doi: 10.1016/j.cmet.2012.12.013.
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Genetics of longevity in model organisms: debates and paradigm shifts.模式生物长寿的遗传学:争论与范式转变。
Annu Rev Physiol. 2013;75:621-44. doi: 10.1146/annurev-physiol-030212-183712. Epub 2012 Nov 26.
8
Superoxide dismutase is dispensable for normal animal lifespan.超氧化物歧化酶对于正常动物寿命来说并非必不可少。
Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5785-90. doi: 10.1073/pnas.1116158109. Epub 2012 Mar 26.
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Temporal requirements of heat shock factor-1 for longevity assurance.热休克因子-1 保证长寿的时间要求。
Aging Cell. 2012 Jun;11(3):491-9. doi: 10.1111/j.1474-9726.2012.00811.x. Epub 2012 Mar 19.
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The cell-non-autonomous nature of electron transport chain-mediated longevity.电子传递链介导的寿命的非自主细胞特性。
Cell. 2011 Jan 7;144(1):79-91. doi: 10.1016/j.cell.2010.12.016.