通过实用的硼-维蒂希反应由醛合成硼酸乙烯酯。
Synthesis of vinyl boronates from aldehydes by a practical boron-Wittig reaction.
作者信息
Coombs John R, Zhang Liang, Morken James P
机构信息
Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.
出版信息
Org Lett. 2015 Apr 3;17(7):1708-11. doi: 10.1021/acs.orglett.5b00480. Epub 2015 Mar 23.
Abstract
A highly stereoselective boron-Wittig reaction between stable and readily accessible 1,1-bis(pinacolboronates) and aldehydes furnishes a variety of synthetically useful di- and trisubstituted vinyl boronate esters.
摘要
稳定且易于获得的1,1-双（频哪醇硼酸酯）与醛之间的高度立体选择性硼-维蒂希反应可提供多种具有合成用途的二取代和三取代乙烯基硼酸酯。
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