Kuffler Damien P
Institute of Neurobiology, University of Puerto Rico, San Juan, Puerto Rico.
Wound Repair Regen. 2015 May-Jun;23(3):312-7. doi: 10.1111/wrr.12284.
Pressure ulcers can be initiated by as little as 2 hours of constant pressure on the ski, that blocks blood circulation causing the skin and underlying tissues to die, leading to an open wound that never heals, but continues to grow in diameter and depth, and frequently jeopardizes patients' lives. Despite the application of many diverse techniques, pressure ulcers remain exceptionally difficult to heal because many ulcer elimination techniques have minimal effects, and although other techniques may appear to be effective, the evidence supporting their efficacy is weak. However, increasing evidence indicates that other techniques, such as the application of platelet-rich plasma, vacuum assisted closure, electrical stimulation, and hyperbaric oxygen therapy are effective and should be substituted for the older techniques. This review describes different standard and novel techniques that have been tested for eliminating pressure ulcers and discusses the relative efficacy of these techniques.
仅2小时的持续皮肤压力就可能引发压疮，这种压力会阻碍血液循环，导致皮肤及皮下组织坏死，形成难以愈合的开放性伤口，伤口直径和深度还会不断扩大，常常危及患者生命。尽管应用了多种不同技术，但压疮仍然极难愈合，因为许多溃疡消除技术效果甚微，而且尽管其他技术看似有效，但其有效性的证据并不充分。然而，越来越多的证据表明，其他技术，如富血小板血浆应用、负压封闭引流、电刺激和高压氧治疗是有效的，应该取代那些旧技术。这篇综述描述了已测试用于消除压疮的不同标准技术和新技术，并讨论了这些技术的相对疗效。
