Huang Shun, Yang Ying, Yu Xiaoli, Wang Yonggang
Department of Nursing.
Liver Cirrhosis Diagnosis and Treatment Center.
Medicine (Baltimore). 2020 Nov 6;99(45):e23079. doi: 10.1097/MD.0000000000023079.
The objective of this current research is to investigate the effectiveness of the nursing intervention of combination gelatin sponge and moist wound healing in treating the pressure ulcers (PUs).
This is a randomized controlled trial to be carried out from January 2021 to May 2021. This trial is implemented in accordance with the SPIRIT Checklist for the randomized researches and was granted through the Ethics Committee of 5th Medical Center of Chinese PLA General Hospital (No. 0624876). This study includes 80 PU participants. The patients meet the following criteria will be included. All participants meet the diagnostic criteria recommended via the National Pressure Ulcer Advisory Panel Society: complete skin defect, no bones, tendons and muscles exposure, no subcutaneous tunnel or scale; the patients selected are between 40 and 60 years old. The patients with the following criteria will be excluded: receiving other treatments that may influence the healing, for instance, radiation therapy and corticosteroids; patients with the complications of infection, malignant tumors, as well as peripheral vascular disease; and patients with serious diseases, containing kidney, cardiac, and liver diseases. The patients are randomly divided into 2 groups, the control group and study group, with 40 members in each group. In control group, the patients are given the routine nursing care. And in study group, the patients are given the nursing of gelatin sponge combined with moist wound-healing. After 28 days, the state of the patients healing is observed closely, containing the dressing change frequency, curative effects, and the end-point efficiency. On the basis of the Pressure Ulcer Healing Scale developed by the American pressure sore expert group, the quantitative scoring can be implemented, and therapeutic effects are assessed.
The variables of clinical result among the groups are illustrated in the Table.
The nursing intervention of gelatin sponge combined with the moist wound- healing may evidently increase the healing efficiency of PU.
researchregistry 6091.
本研究旨在探讨明胶海绵联合湿性愈合护理干预对压疮（PUs）的治疗效果。
这是一项于2021年1月至2021年5月开展的随机对照试验。该试验按照随机研究的SPIRIT清单实施，并获得中国人民解放军总医院第五医学中心伦理委员会批准（编号：0624876）。本研究纳入80例压疮患者。符合以下标准的患者将被纳入。所有参与者均符合美国压疮咨询小组协会推荐的诊断标准：皮肤全层缺损，无骨骼、肌腱和肌肉外露，无皮下隧道或结痂；入选患者年龄在40至60岁之间。符合以下标准的患者将被排除：接受可能影响愈合的其他治疗，如放疗和皮质类固醇；患有感染、恶性肿瘤以及外周血管疾病并发症的患者；患有严重疾病，包括肾脏、心脏和肝脏疾病的患者。患者被随机分为2组，即对照组和研究组，每组40人。对照组给予常规护理。研究组给予明胶海绵联合湿性愈合护理。28天后，密切观察患者的愈合情况，包括换药频率、疗效和终点效率。根据美国压疮专家组制定的压疮愈合量表进行定量评分，并评估治疗效果。
各组间临床结果变量见表。
明胶海绵联合湿性愈合护理干预可显著提高压疮的愈合效率。
researchregistry 6091。
