Department of Gastroenterology, Affiliated Donghua Hospital of Sun Yat-sen University, Dongguan 523110, Guangdong Province, China.
World J Emerg Med. 2015;6(1):23-8. doi: 10.5847/wjem.j.1920-8642.2015.01.004.
The study aimed to estimate the value of embryonal natural orifice transluminal endoscopic surgery (ENOTES) in treating severe acute pancreatitis (SAP) complicated with abdominal compartment syndrome (ACS).
The patients, who were randomized into an ENOTES group and an operative group, underwent ENOTES and laparotomy, respectively. The results and complications of the two groups were compared.
Enterocinesia was observed earlier in the ENOTES group than in the operative group. Acute Physiology and Chronic Health Evaluation II (APACHE II) score of patients in the ENOTES group was lower than that of the operative group on the 1st, 3rd and 5th post-operative day (P<0.05). The cure rate was 96.87% in the ENOTES group, which was statistically different from 78.12% in the operative group (P<0.05). There were significant differences in complications and mortality between the two groups (P<0.01).
Compared with surgical decompression, ENOTES associated with flexible endoscope therapy is an effective and minimal invasive procedure with less complications.
本研究旨在评估经自然腔道内镜手术(NOTES)在治疗伴有腹腔间隔室综合征(ACS)的重症急性胰腺炎(SAP)中的价值。
患者随机分为 NOTES 组和手术组,分别行 NOTES 和剖腹术,比较两组的结果和并发症。
NOTES 组的肠动力恢复时间早于手术组。术后第 1、3、5 天,NOTES 组患者急性生理学与慢性健康状况评分系统 II(APACHE II)评分均低于手术组(P<0.05)。NOTES 组的治愈率为 96.87%,与手术组的 78.12%相比有统计学差异(P<0.05)。两组并发症和死亡率差异有统计学意义(P<0.01)。
与外科减压相比,NOTES 联合软式内镜治疗是一种有效且微创的方法,并发症更少。